最新ニュース Metagenomi (NASDAQ:MGX) 株価情報

Metagenomi

Metagenomi Inc is a genetic medicines company committed to developing curative therapeutics for patients using its proprietary, comprehensive metagenomics-derived genome editing toolbox. The genome editing toolbox includes systems for making small edits such as programmable nucleases, base editors, small RNA-mediated integration systems (RIGS), as well as large gene integration systems including large template RIGS and CRISPR-associated transposases (CASTs). The company is focused on its vivo gene editing for its wholly-owned pipeline while pursuing technology out licensing for ex vivo cell therapy. Its pipeline includes product candidates aimed at addressing disorders like Hemophilia A (through MGX-001), Refractory Hypertension, Cardiovascular diseases, and Wilson's disease, among others.

Metagenomi Inc

MGX Minerals Inc

Gold prices surged to an unprecedented high above $3,300 per ounce on Wednesday as stock market futures declined amid escalating trade tensions between the United States and China.
What Happened: Spot gold jumped 1.72% to $3,306.90, extending its remarkable 23.45% rally since President Donald Trump&#8216;s January inauguration, when the precious metal traded near $2,678.
The rally comes as futures markets signal trouble ahead for equities. Nasdaq-100 futures fell 1.06% to 18,758.75, while S&amp;P 500 futures declined 0.42% to 5,405.25. Dow Jones Industrial Average futures showed minimal loss, down 0.09% to 40,536.
The White House announced late Tuesday that Chinese imports now face tariffs of up to 245% following a series of retaliatory actions between <a href="https://www.benzinga.com/markets/25/04/44831287/trump-administration-imposes-up-to-245-tariff-on-chinese-imports-amid-intensifying-trade-battle">the two economic powers</a>. The tariff war has intensified dramatically since Trump took office, beginning with a 20% levy that has progressively increased through multiple rounds of escalation.
See Also: <a href="https://www.benzinga.com/markets/cryptocurrency/25/04/44832638/despite-unrealized-losses-semler-scientific-plans-500-million-securities-offering-to-boost-bitcoin-holdings">Despite Unrealized Losses, Semler Scientific Plans $500 Million Securities Offering To Boost Bitcoin Holdings</a>
Why It Matters: &#8220;China now faces up to a 245% tariff on imports to the United States as a result of its retaliatory actions,&#8221; according to the White House fact sheet. The latest increase focuses particularly on critical minerals and derivative products that the administration deems essential for U.S. defense <a href="https://www.benzinga.com/markets/25/04/44831287/trump-administration-imposes-up-to-245-tariff-on-chinese-imports-amid-intensifying-trade-battle">capabilities and technological innovation</a>.
The market reaction underscores investor concerns about economic growth prospects as the two largest economies continue their confrontation, driving capital toward traditional safe havens like gold while adding pressure to technology stocks that <a href="https://www.benzinga.com/25/04/44830391/us-stock-futures-nikkei-slip-amid-fresh-nvidia-headwinds-dollar-continues-to-lose-steam">depend heavily on global supply chains</a>.
The Dow Jones fell by approximately 156 points to close at 40,368.96 on Tuesday. The S&amp;P 500, tracked by SPDR S&amp;P 500 (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/SPY#NYSE">SPY</a>), declined 0.17% to 5,396.63, while the Nasdaq Composite, tracked by Invesco QQQ Trust (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/QQQ#NASDAQ">QQQ</a>), edged down 0.05% to 16,823.17.
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</ul>
Disclaimer:&nbsp;This content was partially produced with the help of AI tools and was reviewed and published by Benzinga editors.
Photo courtesy: Shutterstock

Equities

News

Commodities

Markets

Gold Surges Above $3,300 To Record High As US-China Trade War Escalates With 245% Tariff

<a href="https://truthsocial.com/@realDonaldTrump/114347128422370864" title="https://truthsocial.com/@realDonaldTrump/114347128422370864">https://truthsocial.com/@realDonaldTrump/114347128422370864</a>

Macro Economic Events

Politics

Economics

General

President Trump Posted On Truth Social: Japan is coming in today to negotiate Tariffs, the cost of military support, and "TRADE FAIRNESS." I will attend the meeting, along with Treasury & Commerce Secretaries. Hopefully something can be worked out which is good (GREAT!) for Japan and the USA!

Bitcoin's (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/btc/usd">BTC</a>) <a href="https://www.benzinga.com/markets/cryptocurrency/25/04/44627407/gold-overtaking-bitcoin-in-inflation-hedge-strategy-jpmorgan-says">comparative underperformance against gold</a> so far this year may soon flip, with crypto veteran Anthony Pompliano asserting that historical trends point to a coming surge in Bitcoin returns.
What Happened: <a href="https://x.com/APompliano/status/1912119591859298613">Speaking</a> on CNBC's Squawk Box on Tuesday, the founder and CEO of Professional Capital Management said the digital asset is "acting like it wants to go higher" and is likely to leave gold behind in the coming months.
"Bitcoin is down about 10% to start the year. Gold's up 20%. But over a one-year period, they're both up about 35%," Pompliano noted. 
He explained that gold typically leads such rallies, followed by a stronger, delayed move from Bitcoin. 
"When gold runs, about 100 days later, Bitcoin not only catches up — it usually runs much harder," he said.
Pompliano emphasized that central banks and institutional investors still largely lean toward gold during geopolitical crises due to regulatory limitations or ingrained risk behavior. 
However, he believes Bitcoin's historical patterns suggest a more explosive upside lies ahead.
Also Read: <a href="https://www.benzinga.com/top-stories/25/04/44819009/donald-trumps-crypto-footprint-grows-a-monopoly-style-game-may-be-next">Donald Trump&#8217;s Crypto Footprint Grows: A Monopoly-Style Game May Be Next</a>
Why It Matters: The broader conversation also touched on the evolving nature of Bitcoin adoption.
Pompliano pointed to the growing institutional interest via spot Bitcoin ETFs. 
"There was a sovereign wealth fund that said they got Bitcoin exposure through the ETF. That's meaningful," he said, adding that ETF participation reflects price-based exposure without the custodial or geopolitical complexities of holding the asset directly.
When asked about the Biden and Trump administrations' differing policy stances, Pompliano revealed that he recently spoke with Bo Hines, the executive director of the President&#8217;s Advisory Council for Digital Assets, and was told the U.S. government plans <a href="https://www.benzinga.com/markets/cryptocurrency/25/04/44816420/trump-administration-is-only-looking-to-accumulate-bitcoin-bo-hines-says">to actively accumulate Bitcoin</a>.
"Not only are they going to have the Bitcoin strategic reserve, they're going to buy as much Bitcoin as they possibly can," Pompliano said.
He likened this government-level accumulation to corporate strategies, stating, "That's like what Michael Saylor does, just in a different format." 
He added that the funding could come from various sources, including tariff revenue or by reallocating gold reserves.
Pompliano closed by pointing to a generational shift in portfolio thinking: "Many people grew up with a 60-40 portfolio mindset. A lot of younger people don't believe in that model anymore. They're putting Bitcoin into that mix."
Read Next: 
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<li><a href="https://www.benzinga.com/markets/cryptocurrency/25/04/44812762/stablecoins-to-surge-to-2-trillion-by-2028-says-standard-chartered-heres-what-it-means-for-the-dollar">Stablecoins To Surge To $2 Trillion By 2028, Says Standard Chartered: Here&#8217;s What It Means For The Dollar</a></li>
</ul>
Image: Shutterstock

Coverage of Bitcoin, Etherum, Ripple and all the latest digital currencies.

Cryptocurrency

$BTC

Bitcoin To Outperform Gold In Coming Months, Says Anthony Pompliano

Citizens Financial Group (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/CFG#NYSE">CFG</a>) reported quarterly earnings of $0.77 per share which beat the analyst consensus estimate of $0.75 by 2.67 percent.

Earnings

Citizens Financial Group Q1 2025 GAAP EPS $0.77 Beats $0.75 Estimate

ASML Holding NV (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ASML#NASDAQ">ASML</a>) CFO Roger Dassen explained the impact he expects the tariffs to have on the company in 2025 during an analyst call.
What Happened: On Tuesday, following ASML&#8217;s first-quarter earnings, Dassen answered questions regarding the tariffs and their impact on the company&#8217;s performance.
While stating that the situation was still quite dynamic, Dassen outlined the potential fallout that he foresees across four key areas of the company's supply chain.
The first category he says is the tariffs imposed on complete system shipments into the United States. Followed by tariffs on the parts and tools required for field operations within the U.S., which is the second category.
See More: <a href="https://www.benzinga.com/markets/equities/25/04/44832483/tesla-bull-ross-gerber-says-elon-musk-doesnt-care-about-company-anymore-blames-focus-on-other-ventures-for-ev-makers-slump">Tesla Bull Ross Gerber Says Elon Musk &#8216;Doesn&#8217;t Care&#8217; About Company Anymore, Blames Focus On Other Ventures For EV Maker&#8217;s Slump</a>
Third is tariffs on the material imports that it needs to manufacture in its U.S.-based facilities. Dassen notes that the company does &#8220;have some manufacturing capability in the US. So anything related to that would be the third category.&#8221;
Finally, the fourth category pertains to the reciprocal tariffs imposed by other countries on ASML&#8217;s shipments from the United States.
Dassen then mentions the extent to which the tariffs will have an impact on global GDP and on total market demand as another factor to consider. In the end, however, he mentions that the company is doing all it can to ensure that the impact on its finances is &#8220;as limited as possible.&#8221;
Why It Matters: According to ASML&#8217;s 2024 annual report, the company generates a bulk of its sales in China, South Korea, Taiwan, and Japan, at 36%, 23%, 15%, and 4%, respectively. 
These are all countries on which the U.S. has imposed reciprocal tariffs, and while tariffs on all but China are paused, analysts such as Ben Barringer of Quilter Cheviot believe the impact will be &#8220;widespread,&#8221; before adding that it was still too early to tell the kind of effect the company will have to CNBC&#8217;s Squawk Box Europe.
ASML posted a better-than-expected <a href="https://www.benzinga.com/25/04/44832382/nvidia-supplier-asml-beats-revenue-and-eps-estimates-euv-product-mix-performance-milestones-drive-q1-says-ceo">first-quarter performance</a> yesterday, but net bookings witnessed a slowdown, coming in below consensus estimates.
Price Action: The stock is down 4% in premarket trading on Wednesday, and is down over 30% in the past year.
<figure class="wp-block-image size-large"><img loading="lazy" decoding="async" width="1024" height="148" src="https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/16050231/Screenshot-2025-04-16-at-2.30.33-PM-1024x148.png" alt="" class="wp-image-873766" srcset="https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/16050231/Screenshot-2025-04-16-at-2.30.33-PM-1024x148.png 1024w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/16050231/Screenshot-2025-04-16-at-2.30.33-PM-300x44.png 300w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/16050231/Screenshot-2025-04-16-at-2.30.33-PM-768x111.png 768w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/16050231/Screenshot-2025-04-16-at-2.30.33-PM-1536x223.png 1536w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/16050231/Screenshot-2025-04-16-at-2.30.33-PM.png 1600w" sizes="(max-width: 1024px) 100vw, 1024px" /></figure>
According to <a href="https://www.benzinga.com/premium/ideas/benzinga-edge-2#:~:text=Turn%20Market%20Chaos,when%20markets%20rebound">Benzinga&#8217;s Edge Stock Rankings</a>, ASML Holdings scores well on growth but falls short on momentum and value. The stock is not favorable for the short, medium, or long term. Want more insights like this for all stocks? Sign up for Benzinga Edge today.
Read More:
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<li><a href="https://www.benzinga.com/markets/cryptocurrency/25/04/44832638/despite-unrealized-losses-semler-scientific-plans-500-million-securities-offering-to-boost-bitcoin-holdings">Despite Unrealized Losses, Semler Scientific Plans $500 Million Securities Offering To Boost Bitcoin Holdings</a></li>
</ul>
Photo courtesy: Skorzewiak / Shutterstock.com

ASML

ASML Shares Slide After CFO Highlights Tariff-Driven Uncertainty For 2025

Offerings

Kingsoft Announced The Commencement Of An Underwritten Public Offering Of 18.5M Of American Depositary Shares, Each Representing 15 Ordinary Shares Of The Company, Or A Total Of 277.5M Ordinary Shares

Sandvik (OTC:<a class="ticker" href="https://www.benzinga.com/stock/SDVKY#OTC">SDVKY</a>) reported quarterly earnings of $0.28 per share which missed the analyst consensus estimate of $0.29 by 3.45 percent. This is a 6.67 percent decrease over earnings of $0.30 per share from the same period last year. The company reported quarterly sales of $2.74 billion which missed the analyst consensus estimate of $3.00 billion by 8.60 percent. This is a 7.99 percent decrease over sales of $2.98 billion the same period last year.

Earnings Misses

SDVKY

Sandvik Q1 Adj EPS $0.28 Misses $0.29 Estimate, Sales $2.74B Miss $3.00B Estimate

MSPR

MSP Recovery FY2024 Sales Of $18.25M Vs. $7.71M YoY, EPS Loss Of $(359.95) Vs. $(158.02) YoY

Guidance

Autoliv Sees FY25 Organic Sales Growth Of About 2%

Markel Announced It Has Entered Into An Agreement To Purchase The MECO Group Limited, Subject To Regulatory Approval, For An Undisclosed Amount

Autoliv (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/ALV#NYSE">ALV</a>) reported quarterly earnings of $2.15 per share which beat the analyst consensus estimate of $1.67 by 28.74 percent. This is a 36.08 percent increase over earnings of $1.58 per share from the same period last year. The company reported quarterly sales of $2.58 billion which beat the analyst consensus estimate of $2.52 billion by 2.30 percent. This is a 1.41 percent decrease over sales of $2.62 billion the same period last year.

Earnings Beats

Autoliv Q1 Adj $2.15 Beats $1.67 Estimate, Sales $2.58B Beat $2.52B Estimate

The partnership expands eBay's global payment platform capabilities to enhance customer experience and drive operational efficiencies
 &nbsp;

EBAY

eBay Partners With Checkout.com To Boost Global Payments And Enhance Customer Experience

Commerce Bancshares (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CBSH#NASDAQ">CBSH</a>) reported quarterly earnings of $0.98 per share which beat the analyst consensus estimate of $0.94 by 4.26 percent. This is a 19.51 percent increase over earnings of $0.82 per share from the same period last year. The company reported quarterly sales of $428.05 million which beat the analyst consensus estimate of $419.70 million by 1.99 percent. This is a 7.59 percent increase over sales of $397.85 million the same period last year.

CBSH

Commerce Bancshares Q1 EPS $0.98 Beats $0.94 Estimate, Sales $428.05M Beat $419.70M Estimate

A Texas federal judge has ruled against a Biden-era regulation that would have capped <a href="https://www.benzinga.com/news/large-cap/25/03/44482518/major-credit-card-provider-warns-us-consumers-are-spending-less">credit card</a> late fees at $8, terminating a major initiative by the Consumer Financial Protection Bureau (CFPB) to restrict what it labelled "junk fees."
 The decision is being regarded as a legal and political win for financial industry groups that resisted the regulation.
What Happened: U.S. District Judge Mark Pittman <a href="https://storage.courtlistener.com/recap/gov.uscourts.txnd.387342/gov.uscourts.txnd.387342.150.0.pdf">dismissed</a> the CFPB rule, finalized in March 2024, after both the agency and six major business associations agreed it was unlawful. The rule was meant to save consumers an average of $220 a year by limiting late fees.
Pittman ruled that it conflicted with the 2009 Credit Card Accountability and Disclosure Act, which allows fees that are "reasonable and proportional." The lawsuit was filed by the American Bankers Association, U.S. Chamber of Commerce, and many Texas business groups.
See Also: <a href="https://www.benzinga.com/personal-finance/25/03/44353947/trumps-cfpb-overhaul-leaves-consumers-exposed-heres-what-it-means-for-your-money">Trump&#8217;s CFPB Overhaul Leaves Consumers Exposed—Here&#8217;s What It Means For Your Money</a>
Why It Matters: The court's ruling deals a setback to the Biden administration's larger effort to take down what it called predatory consumer charges. Those opposing the rule argued it would backfire.
"It would have resulted in more late payments, lower credit scores, higher interest rates and reduced credit access," the plaintiffs said in a joint statement. They added that the outcome was a victory for financial responsibility and "common sense."
The CFPB's attempt to reformulate the <a href="https://www.benzinga.com/news/earnings/25/04/44811593/bank-of-america-ceo-says-consumer-continues-to-spend-and-maintain-healthy-credit-quality-sticks-to-annual-outlook">credit card fee structure</a> now faces a major hindrance. With rising scrutiny of the agency's authority and legal footing, the future of federal consumer protection efforts hangs in limbo, particularly as calls to limit or even shut down the CFPB gain attention.
Read Next:
<ul>
<li><a href="https://www.benzinga.com/personal-finance/25/04/44778197/a-52-year-old-man-who-owes-money-on-27-credit-cards-gets-an-ultimatum-from-dave-ramsey-chop-them-all-up-every-one-of-them">A 52-Year-Old Man Who Owes Money On 27 Credit Cards Gets An Ultimatum From Dave Ramsey: &#8216;Chop Them All Up. Every One Of Them&#8217;</a></li>
</ul>
Image via Shutterstock

Regulations

Personal Finance

Judge Strikes Down Biden-Era Rule Capping Credit Card Late Fees At $8

Bruker and RECIPE are pioneering the high-throughput ‘chrom-free' ClinDART triple-quad MS platform for robust and cost-effective therapeutic drug monitoring assays

BRKR

Bruker Acquires Majority Stake In RECIPE to Advance Chrom-Free Triple-Quad Assays For Therapeutic Drug Monitoring

BEEM

Beam Global Announced The Sale Of Its First EV ARC Systems In Romania

GeneDx Announced Its Plans To Acquire Fabric Genomics, A Pioneer In Ai-powered Genomic Interpretation For Total Consideration Potentially Up To An Aggregate Of $51M Upon Achievement Of Certain Milestones

Alphabet Inc.'s (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/GOOG#NASDAQ">GOOG</a>) (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/GOOGL#NASDAQ">GOOGL</a>) Google's DeepMind is diving into marine science with a new AI model designed to help researchers decode dolphin communication.
What Happened: Earlier this week, Google DeepMind introduced DolphinGemma, an AI model trained to generate and interpret dolphin-like vocalizations.
Built on Google's open-source Gemma architecture, DolphinGemma was developed in collaboration with the Wild Dolphin Project (WDP), a nonprofit that studies Atlantic spotted dolphins in their natural habitat.
Using data collected from decades of dolphin field recordings, the model can produce sequences that mimic real dolphin sounds.
See Also: <a href="https://www.benzinga.com/markets/equities/25/02/44031714/google-implements-layoffs-in-hr-and-cloud-divisions-as-ai-investment-accelerates-report">Google Implements Layoffs In HR And Cloud Divisions As AI Investment Accelerates: Report</a>
Google says DolphinGemma is efficient enough to run on mobile devices, and WDP plans to test it on the Pixel 9 smartphone. The team previously used a Pixel 6 to collect and analyze dolphin vocalizations, but the Pixel 9 will allow simultaneous execution of AI models and audio-matching algorithms in the field.
The goal is to create a system capable of generating synthetic dolphin vocalizations and listening for a matching "reply," potentially paving the way for two-way interaction with dolphins.
<figure class="wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio"> 
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<iframe loading="lazy" title="DolphinGemma: How Google AI is helping decode dolphin communication" width="500" height="281" src="https://www.youtube.com/embed/T8GdEVVvXyE?start=89&#038;feature=oembed" frameborder="0" allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" referrerpolicy="strict-origin-when-cross-origin" allowfullscreen></iframe>
</div>
</figure>
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Why It's Important: Previously, a 2024 Nature <a href="https://www.nature.com/immersive/d41586-024-04050-5/index.html">report</a> highlighted that AI-powered research has revealed that African savannah elephants (Loxodonta africana) and common marmoset monkeys (Callithrix jacchus) use unique "names" for their peers.
Scientists are also applying machine learning to decode the vocalizations of crows.
Despite recent advances, experts caution that an animal equivalent of Google Translate is still a long way off. According to marine biologist David Gruber, founder of the Cetacean Translation Initiative (CETI), the impressive progress in AI language models stems largely from access to massive datasets where the meanings of human language are already well-established.
Check out more of Benzinga&#8217;s Consumer Tech coverage by&nbsp;<a href="https://www.benzinga.com/topic/consumer-tech" target="_blank" rel="noreferrer noopener">following this link</a>.
Read Next:
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<li><a href="https://www.benzinga.com/markets/equities/25/02/44031320/mark-zuckerbergs-meta-wants-to-do-an-ai-app-but-sam-altman-wants-to-pull-a-reverse-uno-card-maybe-well-do-a-social-app" target="_blank" rel="noreferrer noopener">Mark Zuckerberg's Meta Wants To Do An AI App But Sam Altman Wants To Pull A ‘Reverse Uno' Card: ‘Maybe We'll Do A Social App'</a></li>
</ul>
Disclaimer: This content was partially produced with the help of AI tools and was reviewed and published by Benzinga editors.
Photo courtesy: Photo For Everything / Shutterstock.com

Tech

GOOG

GOOGL

Can AI Talk To Dolphins? Google's DeepMind Creates DolphinGemma To Explore Animal Language

U.S. stock futures declined on Wednesday following a muted day of trading on Tuesday. Futures of major benchmark indices were lower in premarket.
The Donald Trump administration levied a<a href="https://www.benzinga.com/markets/25/04/44831287/trump-administration-imposes-up-to-245-tariff-on-chinese-imports-amid-intensifying-trade-battle"> 245% tariff on China</a> late Tuesday. &#8220;China now faces up to a 245% tariff on imports to the United States as a result of its retaliatory actions,&#8221; stated a White House fact sheet.
Meanwhile, the new U.S. export restrictions halting the shipments of Nvidia Corp.&#8216;s (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NVDA#NASDAQ">NVDA</a>)<a href="https://benzinga.com/25/04/44830406/nvidia-to-take-55-billion-hit-over-china-chip-export-restrictions-but-top-analyst-dan-ives-says-hes-not-overly-concerned-all-part-of-the-high-game-of-poker"> H20 graphics processing units to China</a> were announced. The announcement comes after the U.S. government informed the company on April 9 that it would now require a license to export those chips.
The 10-year Treasury bond yielded 4.31% and the two-year bond was at 3.81%. The CME Group's FedWatch <a href="https://www.cmegroup.com/markets/interest-rates/cme-fedwatch-tool.html">tool&#8217;s </a>projections show markets pricing a 79.9% likelihood of the Federal Reserve keeping the current interest rates unchanged in its May meeting. 
<figure class="wp-block-table is-style-stripes"> 
<table>
<tbody>
<tr>
<td>Futures</td>
<td>Change (+/-)</td>
</tr>
<tr>
<td>Dow Jones</td>
<td>-0.07%</td>
</tr>
<tr>
<td>S&amp;P 500</td>
<td>-0.44%</td>
</tr>
<tr>
<td>Nasdaq 100</td>
<td>-1.08%</td>
</tr>
<tr>
<td>Russell 2000</td>
<td>-0.35%</td>
</tr>
</tbody>
</table>
</figure>
The SPDR S&amp;P 500 ETF Trust (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/SPY#NYSE">SPY</a>) and Invesco QQQ Trust ETF (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/QQQ#NASDAQ">QQQ</a>), which track the S&amp;P 500 index and Nasdaq 100 index, respectively, fell in premarket on Wednesday. The SPY was down 0.67% to $534.02, while the QQQ declined 1.27% to $452.17, according to <a href="https://pro.benzinga.com/dashboard">Benzinga Pro</a> data.
Cues From Last Session:
Weighing on U.S. stocks Tuesday, the consumer discretionary, health care, and consumer staples sectors saw the biggest declines.
Bucking the trend, however, information technology and real estate stocks closed higher.
The market moves came as Citigroup Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/C#NYSE">C</a>) and Bank of America Corp. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BAC#NYSE">BAC</a>) reported better-than-expected first-quarter earnings, while economic data showed a rise in the NY Empire State Manufacturing Index and flat export prices alongside a slight drop in import prices for March.
The Dow closed Tuesday 10.44% below its 52-week peak of 45,073.63. The S&amp;P 500 ended 12.21% off its 6,147.43 high, and the Nasdaq 100 was 15.27% below its 22,222.61 record.
<figure class="wp-block-table is-style-stripes"> 
<table>
<tbody>
<tr>
<td>Index</td>
<td>Performance (+/-)</td>
<td>Value</td>
</tr>
<tr>
<td>Nasdaq Composite</td>
<td>-0.049%</td>
<td>16,823.17</td>
</tr>
<tr>
<td>S&amp;P 500</td>
<td>-0.17%</td>
<td>5,396.63</td>
</tr>
<tr>
<td>Dow Jones</td>
<td>-0.38%</td>
<td>40,368.96</td>
</tr>
<tr>
<td>Russell 2000</td>
<td>0.11%</td>
<td>1,882.92</td>
</tr>
</tbody>
</table>
</figure>
Insights From Analysts:
According to Mona Mahajan of Edward Jones, the stock valuations were not stretched anymore. &#8220;While market returns have been negative this year, the upside is that valuations are now looking more compelling and are no longer stretched, which was a concern coming into this year.&#8221;
She highlighted that all major indexes were trading at or below their 10-year historical forward price-to-earnings multiples, potentially setting the stage for improved long-term returns.
The S&amp;P 500 forward multiple was around 18 times next year&#8217;s earnings forecast, down from a recent high of 22.7 times, while the Nasdaq forward multiple was about 21 times, down from its recent high of 30 times.
&#8220;In our view, the spike in volatility, a reset in valuations, and signs that the worst-case scenario in the trade war appears to be averted suggest that stocks may find some support and try to carve out a bottom. Risks have risen, but a recession is not inevitable in our view, and stocks appear to have already priced in a significant degree of bad outcomes,&#8221; she added.
Jason Goepfert of White Oak Consultancy LLC noted a historical pattern: whenever the VIX fear index drops from above 50 to the 30 level, the S&amp;P 500 has historically achieved 100% positive gains by year-end.
However, he points out that in the most recent such cycle in May 2020, the S&amp;P 500&#8217;s return after a year was 42.96%. Goepfert&#8217;s analysis of similar cycles in 2009, 2002, and 1988 also reveals a short-term median loss of 0.7% for the S&amp;P 500 in the week following the VIX&#8217;s drop to 30.
<figure class="wp-block-embed is-type-rich is-provider-twitter wp-block-embed-twitter"> 
<div class="wp-block-embed__wrapper">
<blockquote class="twitter-tweet" data-width="500" data-dnt="true">The VIX cycle from &gt; 50 to &lt; 30 is on track to trigger today. A bear killer. <a href="https://t.co/rzvdiBw37G">pic.twitter.com/rzvdiBw37G</a>
&mdash; Jason Goepfert (@jasongoepfert) <a href="https://twitter.com/jasongoepfert/status/1912145727448363174?ref_src=twsrc%5Etfw">April 15, 2025</a></blockquote>
<script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script></div>
</figure>
According to an X post by Charlie Bilello of Creative Planning, historical data since 1990 showed that the S&amp;P 500 has delivered an average return of 35% in the year following a VIX close above 50, and 129% over the subsequent five years.
<figure class="wp-block-embed is-type-rich is-provider-twitter wp-block-embed-twitter"> 
<div class="wp-block-embed__wrapper">
<blockquote class="twitter-tweet" data-width="500" data-dnt="true">The <a href="https://twitter.com/search?q=%24VIX&amp;src=ctag&amp;ref_src=twsrc%5Etfw">$VIX</a> closed above 50 last week for the first time since April 2020. In the past, what has that meant for stocks going forward? Video discussion: <a href="https://t.co/YYVlqL4IlH">https://t.co/YYVlqL4IlH</a> <a href="https://t.co/iEy9Wb5myJ">pic.twitter.com/iEy9Wb5myJ</a>
&mdash; Charlie Bilello (@charliebilello) <a href="https://twitter.com/charliebilello/status/1912220992963035233?ref_src=twsrc%5Etfw">April 15, 2025</a></blockquote>
<script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script></div>
</figure>
See Also: <a href="https://www.benzinga.com/money/how-to-trade-futures">How to Trade Futures</a>
Upcoming Economic Data
Here&#8217;s what investors will keep an eye on Wednesday:
<ul>
<li>March&#8217;s U.S. retail sales will be out by 8:30 a.m. ET.</li>
</ul>
<ul>
<li>Industrial production and capacity utilization data for March will be announced at 9:15 a.m. ET.</li>
</ul>
<ul>
<li>Business inventories for February and the home builder confidence index for April will be out by 10:00 a.m. ET.</li>
</ul>
<ul>
<li>Cleveland Fed President Beth Hammack will speak at noon.</li>
</ul>
Stocks In Focus:
<ul>
<li>Abbott Laboratories (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/ABT#NYSE">ABT</a>) rose 0.74% in premarket on Wednesday as it is expected to report earnings before the opening bell. Analysts expect a quarterly earnings of $1.07 per share on revenue of $10.40 billion.</li>
</ul>
<ul>
<li>Travelers Companies Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/TRV#NYSE">TRV</a>) was up 0.076% as Wall Street expects it to report earnings of 80 cents per share on revenue of $10.82 billion before the opening bell.</li>
</ul>
<ul>
<li>Progressive Corp. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/PGR#NYSE">PGR</a>) fell 0.01% as it is expected to report earnings before the opening bell. Analysts expect a quarterly earnings of $4.81 per share on revenue of $21.63 billion.</li>
</ul>
<ul>
<li>ASML Holding NV (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ASML#NASDAQ">ASML</a>) dropped 4.2% despite beating earnings estimates as its revenue and EPS fell on a sequential basis.</li>
</ul>
<ul>
<li>J B Hunt Transport Services Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/JBHT#NASDAQ">JBHT</a>) dropped 6.28% after reporting a 7.6% decline in profit for the first quarter. The company posted quarterly revenue of $2.92 billion, compared to market estimates of $2.90 billion.</li>
</ul>
<ul>
<li>iCAD Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ICAD#NASDAQ">ICAD</a>) surged 72.02% and Radnet Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/RDNT#NASDAQ">RDNT</a>) fell 2.03% after they announced a definitive all-stock merger agreement where RadNet will acquire iCAD.</li>
</ul>
<ul>
<li>La Rosa Holdings (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/LRHC#NASDAQ">LRHC</a>) jumped 119.16% after Nasdaq granted a 180-day extension, until October 6, 2025, to regain the $1.00 minimum bid price for continued listing under &#8216;LRHC&#8217;.</li>
</ul>
Commodities, Gold, And Global Equity Markets:
Crude oil futures were trading higher in the early New York session by 0.60% to hover around $61.70 per barrel.
Gold Spot US Dollar advanced 2.38% to hover around $3,304.35 per ounce. Its fresh record high stood at $3,318 per ounce. The U.S. Dollar Index spot was lower by 0.51% at the 99.7040 level.
Asian markets declined on Wednesday, except India's S&amp;P BSE Sensex, China&#8217;s CSI 300 index. Hong Kong's Hang Seng, Japan's Nikkei 225, Australia's ASX 200, and South Korea's Kospi index ended lower. European markets were also mostly lower in early trade.
Read Next:
<ul>
<li><a href="https://www.benzinga.com/markets/25/04/44831287/trump-administration-imposes-up-to-245-tariff-on-chinese-imports-amid-intensifying-trade-battle">Trump Administration Imposes Up To 245% Tariff On Chinese Imports Amid Intensifying Trade Battle</a></li>
</ul>
Photo courtesy: Shutterstock

Market Summary

Futures

Treasuries

Federal Reserve

Pre-Market Outlook

Analyst Ratings

ICAD

JBHT

LRHC

NVDA

RDNT

US Stock Likely To Open Lower As US-China Tariff War Continues: 'Valuations Are Now Looking More Compelling,' Says Expert

United Airlines Holdings Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/UAL#NASDAQ">UAL</a>) said it will roll back its flight operations this summer as the company readies itself for a decline in air travel.
What Happened: In a full-year forecast released by the company, United Airlines announced it will cut its flight schedule by 4% starting in July, owing to softer customer demand.
The airline also announced it will retire 21 older aircraft from its fleet as well as scale back on off-peak flights on days with lower demand for air travel, which the company says is part of ‘prudent adjustments to the utilization rate of its fleet'.
The airlines also offered two forecasts — one scenario outlined a stable economy whilst the other outlined a ‘recessionary environment'. United said it earned $0.91 per share in Q1 2025.
Why It Matters: The news comes in as United recorded <a href="https://www.benzinga.com/general/travel/25/04/44826858/united-airlines-stock-takes-off-on-q1-earnings-strong-q2-forecast-fy-guidance-for-stable-and-recessionary-environments-impossible-to-predict">over $13.21 billion</a> in revenue for the quarter, amid uncertainty as Donald Trump's tariffs wreak havoc in the global markets.
Delta Airlines <a href="https://www.benzinga.com/general/travel/25/04/44671680/which-us-airline-is-facing-the-strongest-industry-tailwinds">being the leader</a> in the sector, experienced a surge in stock value after the Donald Trump administration announced a 90-day halt on all tariffs, which had cast doubts over the company's 2025 plans.
However, the aviation industry in the U.S. faces uncertainty with China imposing a <a href="https://www.benzinga.com/news/global/25/04/44831116/kimbal-musk-warns-of-boeings-decline-amid-us-china-decoupling-fewer-planes-pricier-parts-and-lost-jobs-as-airbus-gains-ground">halt on all imports </a>of aircraft made by manufacturer Boeing Co. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BA#NYSE">BA</a>) into the country.
Boeing could face another challenge as it grapples with a potential <a href="https://www.benzinga.com/25/04/44811150/faulty-bathroom-latches-could-cost-boeing-34-million-following-faa-directive">$3.4 million in modification costs</a> to its fleet as the FAA proposes an airworthiness report after it reviewed an incident involving a Boeing aircraft where a passenger got stuck in the onboard lavatory.
Price action: UAL stock experienced a 29.79% YTD in value and currently trades for $67.00 on the NASDAQ, according to <a href="https://pro.benzinga.com/dashboard">Benzinga Pro data</a>.
Read Next:
<ul>
<li><a href="https://www.benzinga.com/25/04/44634938/airline-earnings-at-risk-as-demand-dips-amid-weak-business-travel-low-transborder-traffic-doge-cuts-analyst-says">Airline Earnings At Risk As Demand Dips Amid Weak Business Travel, Low Transborder Traffic, DOGE Cuts: Analyst Says</a></li>
</ul>
Photo: Miguel Lagoa / Shutterstock.com

Travel

United Airlines To Cut Back On Flights This Summer As It Anticipates Decline In Demand

Health Care

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Metagenomi to Present at the 43rd Annual J.P. Morgan Healthcare Conference

Management

Metagenomi Announces New Appointment to its Board of Directors

Metagenomi Highlights Progress Across Therapeutic Portfolio and Outlines Anticipated Milestones

Trump's "Stargate AI" Healthcare/Medical Watch: CSDX, IPA, MGX, CDIO

Totus Medicines Appoints Simon Harnest, MSc, BSc, as Chief Financial Officer

Metagenomi to Present at TD Cowen's 45th Annual Health Care Conference

Metagenomi Announces Publication in Nature Communications on Large Gene Integration Advances Using Novel, Compact CRISPR-associated transposase (CAST) Systems

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