最新ニュース MannKind (NASDAQ:MNKD) 株価情報

MannKind

MannKind Corp is a biopharmaceutical company focused on the development and commercialization of inhaled therapeutic products for patients with diseases such as diabetes and pulmonary arterial hypertension. Its approved product, Afrezza (insulin human) Inhalation Powder, is an ultra-rapid-acting inhaled insulin used to improve glycemic control in adults with diabetes. The product consists of a dry powder formulation of human insulin delivered from a small portable inhaler.

MannKind Corp

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Core Scientific, Inc. - Class A Common Stock

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GSX Techedu Inc. American Depositary Shares

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Earnings Scheduled For February 26, 2025

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MNKD

MannKind shares are trading higher after Wells Fargo initiated coverage on the stock with an Overweight rating and announced a price target of $9.

Top Wall Street analysts changed their outlook on these top names. For a complete view of all analyst rating changes, including upgrades and downgrades, please see our <a href="https://www.benzinga.com/analyst-stock-ratings">analyst ratings page</a>.
<ul>
<li>Wells Fargo analyst Tiago Fauth initiated coverage on MannKind Corporation (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MNKD#NASDAQ">MNKD</a>) with an Overweight rating and announced a price target of $9. MannKind shares closed at $6.30 on Thursday. See how other analysts view this stock.</li>
<li>Citigroup analyst Peter Christiansen initiated coverage on S&amp;P Global Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/SPGI#NYSE">SPGI</a>) with a Buy rating and announced a price target of $600. S&amp;P Global shares closed at $486.56 on Thursday. <a href="https://www.benzinga.com/quote/SPGI/analyst-ratings">See how other analysts view this stock</a>.</li>
<li>JP Morgan analyst Alexander Hess initiated coverage on Fair Isaac Corporation (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/FICO#NYSE">FICO</a>) with a Neutral rating and announced a price target of $2150. Fair Isaac shares closed at $2,044.89 on Thursday. <a href="https://www.benzinga.com/quote/FICO/analyst-ratings">See how other analysts view this stock</a>.</li>
<li>HC Wainwright &amp; Co. analyst Andrew Fein initiated coverage on Avidity Biosciences, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/RNA#NASDAQ">RNA</a>) with a Buy rating and announced a price target of $72. Avidity Biosciences shares closed at $31.05 on Thursday. See how other analysts view this stock.</li>
<li>Chardan Capital analyst Rudy Li initiated coverage on Prothena Corporation plc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/PRTA#NASDAQ">PRTA</a>) with a Buy rating and announced a price target of $40. Prothena shares closed at $16.01 on Thursday. <a href="https://www.benzinga.com/quote/PRTA/analyst-ratings">See how other analysts view this stock.</a></li>
</ul>
Considering buying SPGI stock? Here&#8217;s what analysts think: 
<figure class="wp-block-image size-large is-resized"><img loading="lazy" decoding="async" width="1024" height="589" src="https://editorial-assets.benzinga.com/wp-content/uploads/2024/12/20095106/image-183-1024x589.png" alt="" class="wp-image-701945" style="width:585px;height:auto" srcset="https://editorial-assets.benzinga.com/wp-content/uploads/2024/12/20095106/image-183-1024x589.png 1024w,https://editorial-assets.benzinga.com/wp-content/uploads/2024/12/20095106/image-183-300x172.png 300w,https://editorial-assets.benzinga.com/wp-content/uploads/2024/12/20095106/image-183-768x441.png 768w,https://editorial-assets.benzinga.com/wp-content/uploads/2024/12/20095106/image-183.png 1117w" sizes="(max-width: 1024px) 100vw, 1024px" /></figure>
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This S&P Global Analyst Begins Coverage On A Bullish Note; Here Are Top 5 Initiations For Friday

Wells Fargo analyst Tiago Fauth initiates coverage on MannKind (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MNKD#NASDAQ">MNKD</a>) with a Overweight rating and announces Price Target of $9.

Price Target

Analyst Ratings

Wells Fargo Initiates Coverage On MannKind with Overweight Rating, Announces Price Target of $9

RBC Capital analyst Gregory Renza upgrades MannKind (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MNKD#NASDAQ">MNKD</a>) from Sector Perform to Outperform and raises the price target from $7 to $10.

Upgrades

RBC Capital Upgrades MannKind to Outperform, Raises Price Target to $10

MannKind Corporation (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MNKD#NASDAQ">MNKD</a>) are trading lower Monday. The company released its six-month results from its Phase 3 INHALE-1 pediatric diabetes trial. Here&#8217;s what <a href="https://www.benzinga.com/quote/MNKD/news">you need to know</a>.
What To Know: The trial investigated the use of Afrezza (insulin human) Inhalation Powder in children and adolescents aged 4 to 17 years. Its primary endpoint was a non-inferior change in HbA1c levels after 26 weeks of treatment. 
The results showed that, while Afrezza met the non-inferiority criteria based on a modified intent-to-treat (mITT) analysis, a full intent-to-treat (ITT) analysis did not meet the predetermined non-inferiority margin, largely due to the variability introduced by one non-compliant patient. Despite this, the mITT analysis supported Afrezza&#8217;s non-inferiority to multiple daily injections (MDI) of rapid-acting insulin.
The study also showed no significant differences in lung function between the Afrezza and MDI groups, with both treatment groups maintaining stable FEV1 levels over the 26-week period. No major safety concerns, including hypoglycemia, were noted between the two treatment regimens.
Despite the encouraging efficacy and safety outcomes, the stock&#8217;s decline reflects investor cautiousness, as the company now plans to meet with the U.S. Food and Drug Administration (FDA) in the first half of 2025 regarding a supplemental new drug application (sNDA) for Afrezza's use in pediatric populations. This meeting is crucial for the potential next steps in expanding the treatment&#8217;s approval, which may contribute to further volatility in the stock price depending on the regulatory response.
MNKD Price Action: MannKind shares were down 4.28% at $6.27 at the time of writing, according to <a href="https://pro.benzinga.com/dashboard">Benzinga Pro.</a>
<figure class="wp-block-image size-large is-resized"><a href="https://bzresearch.myclickfunnels.com/benzinga-pro-content-webinar-registration/?utm_source=BZprocontent121624&amp;t=be2bearmibe3na1"><img loading="lazy" decoding="async" width="1024" height="545" src="https://editorial-assets.benzinga.com/wp-content/uploads/2024/12/16154357/MNKD-1024x545.png" alt="" class="wp-image-694664" style="width:453px;height:auto" srcset="https://editorial-assets.benzinga.com/wp-content/uploads/2024/12/16154357/MNKD-1024x545.png 1024w,https://editorial-assets.benzinga.com/wp-content/uploads/2024/12/16154357/MNKD-300x160.png 300w,https://editorial-assets.benzinga.com/wp-content/uploads/2024/12/16154357/MNKD-768x408.png 768w,https://editorial-assets.benzinga.com/wp-content/uploads/2024/12/16154357/MNKD.png 1256w" sizes="(max-width: 1024px) 100vw, 1024px" /></a></figure>
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Image Via Shutterstock.

Movers

MannKind Shares Are falling Today: What's Going On?

Biotech

Health Care

General

MannKind Announced Six-month Results From Its Phase 3 Inhale-1 Study Of Afrezza (Insulin Human) Inhalation Powder In Children And Adolescents (Aged 4-17 Years). MannKind Expects To Submit A Request For Supplemental New Drug Application Meeting With FDA In 1H 2025

The CDSCO decision follows existing approvals in the United States and Brazil.

MannKind, Cipla Report CDSCO In India Has Approved Afrezza (Insulin Human) Inhalation Powder In Adults

MannKind (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MNKD#NASDAQ">MNKD</a>) reported quarterly earnings of $0.06 per share which beat the analyst consensus estimate of $0.03 by 100 percent. This is a 200 percent increase over earnings of $0.02 per share from the same period last year. The company reported quarterly sales of $70.079 million which missed the analyst consensus estimate of $74.500 million by 5.93 percent. This is a 36.73 percent increase over sales of $51.253 million the same period last year.

Earnings Beats

Earnings Misses

MannKind Q3 2024 Adj. EPS $0.06 Beats $0.03 Estimate, Sales $70.079M Miss $74.500M Estimate

MannKind Corporation (NASDAQ:<a href="https://www.benzinga.com/stock/MNKD#NASDAQ">MNKD</a>), a company focused on the development and commercialization of innovative inhaled therapeutic products and devices for patients with endocrine and orphan lung diseases, today announced the successful completion of its first-in-human Phase 1 study of nintedanib DPI (MNKD-201) for pulmonary fibrotic diseases, including idiopathic pulmonary fibrosis (IPF).
"These compelling results support advancing the development of nintedanib DPI for patients living with IPF, a chronic and progressive fibrotic lung disease with limited treatment options," said Michael Castagna, PharmD, Chief Executive Officer for MannKind Corporation. "We look forward to discussing the Phase 1 trial results and our proposed late-stage development program at an end of phase 1 meeting with the FDA, planned for the first half of 2025."
The key highlights of the study included:
<ul>
<li>Nintedanib DPI was shown to be safe and well tolerated in healthy volunteers with the tested doses and study duration</li>
<li>Participants did not experience typical adverse events seen with oral nintedanib; specifically, no GI or neurologic adverse events (AEs) were reported</li>
<li>Two types of AEs noted - cough and drop in FEV-1
<ul>
<li>These AEs were mild, transient, and fully recovered</li>
<li>These AEs were not dose-dependent and there was no pattern of recurrence or worsening with repeated dosing</li>
<li>No bronchospasm, wheezing, other symptoms, or change in vital signs were reported</li>
</ul>
</li>
<li>No serious adverse events or study drug discontinuation &nbsp;</li>
</ul>
The completed Phase 1 was a single-site, randomized, placebo-controlled, single- (n=24) and multiple-ascending dose (n=16) study in healthy adult (older than 40 years old) participants. The primary objective of the study was to evaluate the safety and tolerability of nintedanib DPI. The secondary study objective was to evaluate the pharmacokinetics (PK) of MNKD-201.

MannKind Completes Phase 1 Trial of Inhaled Therapy for Lung Disease, Results Show Nintedanib DPI Safe and Tolerable

MannKind Corporation (NASDAQ:<a href="https://www.benzinga.com/stock/MNKD#NASDAQ">MNKD</a>), a company focused on the development and commercialization of inhaled therapeutic products and devices for patients with endocrine and orphan lung diseases, today announced top-level 30-week results from its Phase 4 INHALE-3 study, in which additional patients living with type 1 diabetes achieved target A1c levels during the extension phase. The completer analysis which included all people on inhaled insulin, evaluated two separate groups – one that utilized Afrezza&#xAE; (plus basal insulin) over 30 weeks, and a second group of patients who switched to Afrezza at week 17 from usual care, defined as multiple daily injections (MDI), an automated insulin delivery system, (AID) or a pump without automation.
"The data from the extension phase of this study showed that more people living with T1D are able to reach target A1c levels when they remain on Afrezza (plus basal insulin) or switch to Afrezza from usual care – whether they are using multiple daily injections or pumps," said Michael Castagna, PharmD, Chief Executive Officer for MannKind Corporation. "We believe this data demonstrates to healthcare practitioners that Afrezza is an effective tool for their patients who want to improve their glycemic control."
Key Findings: There was continued improvement in the Afrezza (plus degludec)-treated group, with additional subjects achieving A1c &lt;7% at 30 weeks – a 100% increase from baseline:
&nbsp;<img src="https://ml.globenewswire.com/Resource/Download/31d76640-1047-4108-b133-36b48e91775d/image1.jpg" alt="Afrezza Group Change in HbA1c from Randomization to 30 Weeks" /> &nbsp;&nbsp;
<img src="https://ml.globenewswire.com/Resource/Download/650dc7f2-1e72-487b-9047-d0fdce0a795f/image2.jpg" alt="Afrezza Group Participants Meeting HbA1c Target" /> &nbsp;
Switching from usual care to Afrezza (plus degludec) at week-17 allowed more than double the subjects to achieve A1c &lt;7% at week-30, compared to the number at goal at week-17: &nbsp;
<img src="https://ml.globenewswire.com/Resource/Download/040e275d-bd09-4b8c-abff-4b7d76b32321/image3.jpg" alt="HbA1c Change from 17 Weeks to 30 Weeks in Usual Care-to-Afrezza Subjects" /> &nbsp;
"With the positive data received at both 17- and 30-weeks, we continue to affirm that Afrezza is an important option for adult patients managing their diabetes," said Dr. Kevin Kaiserman, Senior Vice President, Therapeutic Area Head, Endocrine Diseases for MannKind Corporation. "We look forward to discussing more details of the 30-week study results at ATTD next March and additional conferences in 2025."
About the INHALE-3 Study The INHALE-3 study is a 17-week, randomized controlled trial with a 13-week extension conducted across 19 U.S. sites. The study, which enrolled 141 patients (123 randomized), assigned participants over 18 years of age with T1D who are using MDI, an automated insulin delivery system, or a pump without automation to either continue their standard of care or initiate an insulin regimen of a daily basal injection plus Afrezza for boluses (mealtime and corrections). Subjects utilizing Afrezza (inhaled insulin) received a higher initial conversion dose than in the current U.S. product label. Both arms utilized continuous glucose monitoring to assess glucose control.
The randomized control trial (RCT) included an inhaled insulin group that began with 62 subjects at randomization and 57 at 17 weeks; the usual care group consisted of 61subjects at randomization and 58 at 17 weeks. The <a href="https://www.globenewswire.com/Tracker?data=TI60SziG0RhGZNEA5RI2SJ5ByKAZ7RbYuekeJ4VNFdyn2xJj7vBxn3F1-ieEQnO_haT6t32oFEy-0HuRk4_YqF1w6xZ4QG5Vq_qGtjFhAKH-ObJkQ_nROK_nTn749E48SDxVPIHJQZPkq3agscXzSjsIkJuglZTvKZa3fJITomoch34bhIuLQJbRMPJvbU6oq7Efby3cxy80hZr4zXFHiWXh-kDMlt4UXgABv72TMT0DNwhHeq6tMYBhdB2dWGWVGGclGx806ZRo4dt9YWUBB2AZ6kwvPEMjuxGT6xf37DT6upl-k8vHw1S3D5Xx8l6qM1eVl5_t9eDJkz41IDAiTjT7WxneHIUTh1yzQM0IGF6jYv9WW6wWDtHaEfOTPy0f">17-week results</a> previously shared that the study met its primary efficacy endpoint of a non-inferior change in HbA1c between baseline and week 17 compared to the usual care group. At 17 weeks, those who utilized Afrezza (plus basal insulin) continued with it through the extension phase, and those who were on usual care switched over to Afrezza to week 30. The extension phase started with 45 subjects from the inhaled insulin group and 43 completed the extension; the usual care-to-Afrezza group started with 49 in the extension, with 42 completing. There was no control group in the extension phase. A1c levels were obtained at baseline, 17 and 30-weeks.
<img src="https://ml.globenewswire.com/Resource/Download/72bbb5f4-f42f-4a1e-9121-3d4ff8c57790/image4.jpg" alt="Study Design INHALE-3" /> &nbsp;
More information on the INHALE-3 study is available at: <a href="https://www.globenewswire.com/Tracker?data=TRJc0HFwHf9_Kd31JrPug7XoLBMSmDbAWnUCKY-t9n7aMjvxsMn0IfLNAA99yQVgRXIIild8Mlane3Zvviwem0w91-MGoivCHDQTtc7EpuSQSWoanyhL7ZA3TB42YYCfgBJFxSIQB16YFBWsgki96R-DwMXgg29ToMS0uRhrLPd_gESnGiYIB0KOOSj8aGxdgXRWIml6z177svbbki5QOQ==">ClinicalTrials.gov(NCT05904743)</a>.

MannKind's Afrezza Demonstrates A1c Control In Diabetes Patients During MannKind's Phase 4 Trial

This whale alert can help traders discover the next big trading opportunities.
Whales are entities with large sums of money and we track their transactions here at Benzinga on our options activity scanner.
Traders often look for circumstances when the market estimation of an option diverges away from its normal worth. Abnormal amounts of trading activity could push option prices to hyperbolic or underperforming levels. 
Below are some instances of options activity happening in the Health Care sector: 
<table>
<thead>
<tr>
<th>Symbol</th>
<th>PUT/CALL</th>
<th>Trade Type</th>
<th>Sentiment</th>
<th>Exp. Date</th>
<th>Strike Price</th>
<th>Total Trade Price</th>
<th>Open Interest</th>
<th>Volume</th>
</tr>
</thead>
<tbody>
<tr>
<td>PFE</td>
<td>CALL</td>
<td>SWEEP</td>
<td>BULLISH</td>
<td>01/17/25</td>
<td>$32.50</td>
<td>$70.5K</td>
<td>38.1K</td>
<td>2.5K</td>
</tr>
<tr>
<td>BMY</td>
<td>CALL</td>
<td>SWEEP</td>
<td>BEARISH</td>
<td>10/04/24</td>
<td>$51.00</td>
<td>$32.5K</td>
<td>829</td>
<td>797</td>
</tr>
<tr>
<td>BNTX</td>
<td>CALL</td>
<td>SWEEP</td>
<td>BULLISH</td>
<td>10/18/24</td>
<td>$120.00</td>
<td>$34.5K</td>
<td>1.3K</td>
<td>625</td>
</tr>
<tr>
<td>CI</td>
<td>PUT</td>
<td>SWEEP</td>
<td>BULLISH</td>
<td>09/27/24</td>
<td>$355.00</td>
<td>$71.7K</td>
<td>16</td>
<td>505</td>
</tr>
<tr>
<td>TGTX</td>
<td>PUT</td>
<td>SWEEP</td>
<td>BEARISH</td>
<td>01/17/25</td>
<td>$40.00</td>
<td>$137.7K</td>
<td>2</td>
<td>383</td>
</tr>
<tr>
<td>JNJ</td>
<td>CALL</td>
<td>SWEEP</td>
<td>BEARISH</td>
<td>12/20/24</td>
<td>$175.00</td>
<td>$45.4K</td>
<td>513</td>
<td>382</td>
</tr>
<tr>
<td>BHVN</td>
<td>PUT</td>
<td>TRADE</td>
<td>BEARISH</td>
<td>10/18/24</td>
<td>$45.00</td>
<td>$48.4K</td>
<td>74</td>
<td>365</td>
</tr>
<tr>
<td>VKTX</td>
<td>CALL</td>
<td>TRADE</td>
<td>NEUTRAL</td>
<td>11/15/24</td>
<td>$60.00</td>
<td>$189.7K</td>
<td>4.5K</td>
<td>172</td>
</tr>
<tr>
<td>GMED</td>
<td>PUT</td>
<td>SWEEP</td>
<td>BEARISH</td>
<td>12/20/24</td>
<td>$70.00</td>
<td>$31.6K</td>
<td>7</td>
<td>122</td>
</tr>
<tr>
<td>MNKD</td>
<td>CALL</td>
<td>SWEEP</td>
<td>BULLISH</td>
<td>11/15/24</td>
<td>$3.50</td>
<td>$30.0K</td>
<td>121</td>
<td>100</td>
</tr>
</tbody>
</table>

<h2>Explanation</h2>
These itemized elaborations have been created using the accompanying table. 
• For PFE (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/PFE#NYSE">PFE</a>), we notice a call option sweep that happens to be bullish, expiring in 116 day(s) on January 17, 2025. This event was a transfer of 1500 contract(s) at a $32.50 strike. This particular call needed to be split into 47 different trades to become filled. The total cost received by the writing party (or parties) was $70.5K, with a price of $47.0 per contract. There were 38163 open contracts at this strike prior to today, and today 2583 contract(s) were bought and sold. 
• Regarding BMY (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BMY#NYSE">BMY</a>), we observe a call option sweep with bearish sentiment. It expires in 11 day(s) on October 4, 2024. Parties traded 500 contract(s) at a $51.00 strike. This particular call needed to be split into 24 different trades to become filled. The total cost received by the writing party (or parties) was $32.5K, with a price of $65.0 per contract. There were 829 open contracts at this strike prior to today, and today 797 contract(s) were bought and sold. 
• Regarding BNTX (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BNTX#NASDAQ">BNTX</a>), we observe a call option sweep with bullish sentiment. It expires in 25 day(s) on October 18, 2024. Parties traded 150 contract(s) at a $120.00 strike. This particular call needed to be split into 19 different trades to become filled. The total cost received by the writing party (or parties) was $34.5K, with a price of $230.0 per contract. There were 1345 open contracts at this strike prior to today, and today 625 contract(s) were bought and sold. 
• Regarding CI (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/CI#NYSE">CI</a>), we observe a put option sweep with bullish sentiment. It expires in 4 day(s) on September 27, 2024. Parties traded 239 contract(s) at a $355.00 strike. This particular put needed to be split into 15 different trades to become filled. The total cost received by the writing party (or parties) was $71.7K, with a price of $300.0 per contract. There were 16 open contracts at this strike prior to today, and today 505 contract(s) were bought and sold. 
• For TGTX (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/TGTX#NASDAQ">TGTX</a>), we notice a put option sweep that happens to be bearish, expiring in 116 day(s) on January 17, 2025. This event was a transfer of 82 contract(s) at a $40.00 strike. This particular put needed to be split into 12 different trades to become filled. The total cost received by the writing party (or parties) was $137.7K, with a price of $1680.0 per contract. There were 2 open contracts at this strike prior to today, and today 383 contract(s) were bought and sold. 
• For JNJ (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/JNJ#NYSE">JNJ</a>), we notice a call option sweep that happens to be bearish, expiring in 88 day(s) on December 20, 2024. This event was a transfer of 329 contract(s) at a $175.00 strike. This particular call needed to be split into 11 different trades to become filled. The total cost received by the writing party (or parties) was $45.4K, with a price of $138.0 per contract. There were 513 open contracts at this strike prior to today, and today 382 contract(s) were bought and sold. 
• For BHVN (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BHVN#NYSE">BHVN</a>), we notice a put option trade that happens to be bearish, expiring in 25 day(s) on October 18, 2024. This event was a transfer of 149 contract(s) at a $45.00 strike. The total cost received by the writing party (or parties) was $48.4K, with a price of $325.0 per contract. There were 74 open contracts at this strike prior to today, and today 365 contract(s) were bought and sold. 
• Regarding VKTX (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/VKTX#NASDAQ">VKTX</a>), we observe a call option trade with neutral sentiment. It expires in 53 day(s) on November 15, 2024. Parties traded 150 contract(s) at a $60.00 strike. The total cost received by the writing party (or parties) was $189.7K, with a price of $1265.0 per contract. There were 4588 open contracts at this strike prior to today, and today 172 contract(s) were bought and sold. 
• For GMED (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/GMED#NYSE">GMED</a>), we notice a put option sweep that happens to be bearish, expiring in 88 day(s) on December 20, 2024. This event was a transfer of 102 contract(s) at a $70.00 strike. This particular put needed to be split into 31 different trades to become filled. The total cost received by the writing party (or parties) was $31.6K, with a price of $310.0 per contract. There were 7 open contracts at this strike prior to today, and today 122 contract(s) were bought and sold. 
• For MNKD (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MNKD#NASDAQ">MNKD</a>), we notice a call option sweep that happens to be bullish, expiring in 53 day(s) on November 15, 2024. This event was a transfer of 100 contract(s) at a $3.50 strike. This particular call needed to be split into 5 different trades to become filled. The total cost received by the writing party (or parties) was $30.0K, with a price of $300.0 per contract. There were 121 open contracts at this strike prior to today, and today 100 contract(s) were bought and sold. 
Options Alert Terminology 
 - Call Contracts: The right to buy shares as indicated in the contract. 
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10 Health Care Stocks With Whale Alerts In Today's Session

Japan's Pharmaceuticals And Medical Devices Agency Cleared MannKind's Phase 3 Study (ICoN-1) Of Clofazimine Inhalation Suspension For Nontuberculous Mycobacterial Lung Disease. The Global Study Is Now Cleared By To Proceed In Four Countries With A Fifth (Taiwan) Expected In 4Q 2024

MannKind shares are trading higher after Oppenheimer maintained an Outperform rating on the stock and raised its price target from $10 to $12.

U.S. stocks were mixed, with the Dow Jones index gaining around 50 points on Wednesday.
Shares of Kohl&#8217;s Corporation (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/KSS#NYSE">KSS</a>) rose during Wednesday's session following better-than-expected <a href="https://www.benzinga.com/news/earnings/24/08/40599429/kohls-q2-earnings-profit-beat-inventory-decline-margin-growth-and-more">second-quarter financial results.</a>
The company reported a net sales decline of 4.2% Y/Y to $3.525 billion, with comparable sales for the quarter decreasing 5.1% Y/Y. Total revenue stood at $3.732 billion. The analyst consensus estimate was $3.583 billion. EPS was 59 cents, beating the analyst consensus estimate of 44 cents.
Kohl&#8217;s shares climbed 5.6% to $20.71 on Wednesday.
Here are some other big stocks recording gains in today's session.
<ul>
<li>Waldencast plc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/WALD#NASDAQ">WALD</a>) jumped 41.5% to $4.0920 after the company reported second-quarter revenue growth.</li>
<li>AeroVironment, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AVAV#NASDAQ">AVAV</a>) gained 17.6% to $209.40 after multiple analysts upgraded the stock and raised their price targets.</li>
<li>VNET Group, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/VNET#NASDAQ">VNET</a>) gained 17.1% to $2.34 following second-quarter results.</li>
<li>Xiao-I Corporation (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AIXI#NASDAQ">AIXI</a>) rose 12.3% to $5.45.</li>
<li>Bioceres Crop Solutions Corp. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BIOX#NASDAQ">BIOX</a>) climbed 12.1% to $11.32. Bioceres Crop Solutions received green light for cultivation of Drought Tolerant HB4 Wheat in the United States.</li>
<li>Ambarella, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AMBA#NASDAQ">AMBA</a>) surged 11.3% to $58.82 after the company reported better-than-expected second-quarter adjusted EPS and sales.</li>
<li>Box, Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BOX#NYSE">BOX</a>) gained 10.1% to $31.73 after the company reported better-than-expected second-quarter financial results and issued FY25 guidance above estimates.</li>
<li>MannKind Corporation (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MNKD#NASDAQ">MNKD</a>) jumped 10.2% to $5.93. Oppenheimer analyst Steven Lichtman maintained MannKind with an Outperform and raised the price target from $10 to $12.</li>
<li>Westrock Coffee Company (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/WEST#NASDAQ">WEST</a>) gained 9.9% to $9.35. Westrock Coffee Company commenced warrant exchange offer and consent solicitation.</li>
<li>The Hain Celestial Group, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/HAIN#NASDAQ">HAIN</a>) gained 10.2% to $8.93. Hain Celestial Group, on Tuesday, reported better-than-expected quarterly adjusted EPS results</li>
<li>AvePoint, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AVPT#NASDAQ">AVPT</a>) jumped 8.5% to $11.69 after the company announced it commenced an offer to purchase all outstanding public warrants to purchase shares of its common stock at $2.50 per share without interest.</li>
<li>Chewy, Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/CHWY#NYSE">CHWY</a>) gained 8.2% to $28.04 following quarterly results.</li>
<li>Concentrix Corporation (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CNXC#NASDAQ">CNXC</a>) gained 4.4% to $75.49. B of A Securities analyst Ruplu Bhattacharya upgraded Concentrix from Underperform to Neutral and raised the price target from $65 to $85.</li>
<li>Bristol-Myers Squibb Company (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BMY#NYSE">BMY</a>) rose 3.3% to $49.68.</li>
</ul>
Now Read This: 
<ul>
<li><a href="https://www.benzinga.com/news/24/08/40600771/ambarella-to-rally-around-61-here-are-10-top-analyst-forecasts-for-wednesday">Ambarella To Rally Around 61%? Here Are 10 Top Analyst Forecasts For Wednesday</a></li>
</ul>

Intraday Update

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Kohl's Posts Upbeat Q2 Earnings, Joins Box, Waldencast, AeroVironment And Other Big Stocks Moving Higher On Wednesday

Oppenheimer analyst Steven Lichtman maintains MannKind (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MNKD#NASDAQ">MNKD</a>) with a Outperform and raises the price target from $10 to $12.

Oppenheimer Maintains Outperform on MannKind, Raises Price Target to $12

MannKind Q2 2024 Adj. EPS $0.05 Beats $0.01 Estimate, Sales $72.386M Beat $64.813M Estimate

Mannkind Announced The Launch Of An Educational Website Designed To Raise Awareness Of Nontuberculous Mycobacterial (NTM) Lung Disease

&nbsp;MannKind Corporation (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MNKD#NASDAQ">MNKD</a>), a company focused on the development and commercialization of inhaled therapeutic products and devices for patients with endocrine and orphan lung diseases, today announced positive 17-week results from the INHALE-3 study, a Phase 4 U.S. clinical trial evaluating Afrezza&reg;&nbsp;(plus basal insulin) vs. usual care (defined as multiple daily injections (MDI), an automated insulin delivery system, (AID) or a pump without automation) utilizing a higher initial conversion dose from mealtime injectable insulin to inhaled insulin. The study, which was presented by the INHALE-3 investigational team at the American Diabetes Association&#39;s (ADA) 84th&nbsp;Scientific Sessions in Orlando, met its primary efficacy endpoint of a non-inferior change in HbA1c between baseline and week 17 compared to the usual care group.&nbsp;&nbsp;
Key sub-analysis findings included:
<ul>
<li>More subjects utilizing inhaled insulin achieved glycemic targets:
<ul>
<li>30%&nbsp;of inhaled insulin group reached &lt;7%&nbsp;(HbA1c) at 17 weeks vs.&nbsp;17%&nbsp;of the usual care group</li>
<li>21%&nbsp;of inhaled insulin group vs.&nbsp;0%&nbsp;of usual care group met A1c goal of &lt;7%&nbsp;if baseline was &gt;7%</li>
<li>24%&nbsp;of the Afrezza group and&nbsp;13%&nbsp;of the usual care group achieved TIR above&nbsp;70%&nbsp;with no increased hypoglycemia in the inhaled insulin group</li>
</ul>
</li>
<li>No difference in CGM-measured hypoglycemia between the groups</li>
<li>Study helps to establish a titrated basal-bolus ratio that is approximately 70/30 inhaled insulin to basal vs. 50/50 for usual care</li>
<li>While more people met the glycemic target of A1c (less than&nbsp;7%) with Afrezza, some subjects worsened when switching from usual care to inhaled insulin, potentially due to missing doses of inhaled insulin during the day and/or underdosing going into bedtime</li>
<li>More than&nbsp;50%&nbsp;of subjects at the end of the study expressed an interest in continuing to use Afrezza</li>
</ul>

Reported Earlier, MannKind's Inhaled Insulin Afrezza Shows Results in 17-Week Study

Rodman &amp; Renshaw analyst Brandon Folkes initiates coverage on MannKind (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MNKD#NASDAQ">MNKD</a>) with a Buy rating and announces Price Target of $8.

Rodman & Renshaw Initiates Coverage On MannKind with Buy Rating, Announces Price Target of $8

Press Releases

MannKind Successfully Completes Phase 1 Trial of Nintedanib DPI for Pulmonary Fibrotic Diseases

MannKind to Present at 2024 UBS Healthcare Conference

MannKind Corporation Reports 2024 Third Quarter Financial Results and Provides Business Update

CDSCO Approves Afrezza® (insulin human) Inhalation Powder in India

MannKind Announces Six-Month Results From Phase 3 INHALE-1 Pediatric Diabetes Trial Utilizing Inhaled Insulin (Afrezza®)

MannKind Corporation Announces Exchange of Convertible Notes for Stock and Cash

Management

MannKind Expands Executive Leadership Team

MannKind to Present at Upcoming Investor Conferences

MannKind Corporation to Hold 2024 Fourth Quarter and Full Year Financial Results Conference Call on February 26, 2025

MannKind Corporation Reports Fourth Quarter and Full Year 2024 Financial Results and Provides Business Update

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