オプションチェーンは、Relmada Therapeuticsの株式オプションの主要データを様々な行使価格と満期日で表示します。トレーダーはこの情報を使用して、潜在的な取引を分析し、Relmada Therapeuticsの市場センチメントを評価します。.

Relmada Therapeutics (NASDAQ:RLMD) 株価情報, オプションチェーン

Relmada Therapeutics

Relmada Therapeutics Inc is a clinical-stage biotechnology company. It is engaged in developing chemical entities with novel versions of drug products that address areas of high unmet medical need in the treatment of central nervous system diseases. The company is focused on the development of esmethadone (d-methadone, dextromethadone, REL-1017), an N-methyl-D-aspartate (NMDA) receptor antagonist. Its lead product candidate, esmethadone, is an oral agent for the treatment of depression and other potential indications.

Relmada Therapeutics, Inc. - Common Stock

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One of the benefits&nbsp;<a href="https://substack.com/redirect/1b7f3cf6-9b8c-48b8-9e8c-657e8bb35809?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" rel="noreferrer noopener" target="_blank">of aging</a>&nbsp;as an investor is that you accumulate invaluable experience and perspective by living through a lot of very bad economic and financial market events.
These include events when, in the moment, it felt like things had permanently taken a turn for the worse. But time after time, you're reminded that you can't keep the U.S. economy and stock market down for very long.
I like to reflect on those events and recall the unpleasant memories because it helps me better process current and future periods of turmoil and crisis. And the more I reflect, the more I feel like I understand why we keep bouncing back.
<h2 class="wp-block-heading">From the Asian Financial Crisis to the COVID-19 Pandemic </h2>
In the late 1990s, I was just another immature high school kid without many cares in the world. I didn't really keep up with current events. But I remember the Asian Financial Crisis because it was one of the topics in prayers my dad would give at his church in Kentucky. I'll never forget hearing "IMF" come up in those Korean prayers because it was so unusual.
Among other things, the Korean won collapsed by more than half against the U.S. dollar over a very short period at the time. This was a particularly big problem for immigrants closely tied to family back in Korea. I didn't quite understand it at the time, but I remember the mood being disturbingly gloomy for a while.
<figure class="wp-block-image"><a href="https://substack.com/redirect/8c96a367-2e63-438d-a2f7-10c8651a8053?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" target="_blank" rel="noreferrer noopener"><img decoding="async" src="https://ci3.googleusercontent.com/meips/ADKq_NbINJfv5qQh_mHfNAY3Ren2hmfavqULpETqyrT62IAKgBp1GuHcKsWWczq82QUGEIHKukQLVGfPH60szFIs7o2ULNAs2hI74Ykf5yqRx7-ZiP7ih17uwpGn70blunqyGROIAeb-WAQbjArVL5At4St4X3wNc3cE9bHDcdNrbYLzgpxNuZiBX4vUCCXPynbm4By4skuDjxD91-tMivdp90eXPcrjLnj3cJIohK7mOdJejOWbZW1xdoXzAbbeUtDjWF9Q9G08Om8EcfTbZNI2486pcqWJo12NH9WosBIzTY-Wix9XXmZWh-3R=s0-d-e1-ft#https://substackcdn.com/image/fetch/w_1100,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa5a023c5-705e-4037-918a-edf40c616438_939x450.png" alt="" /></a><figcaption class="wp-element-caption">The Asian Financial Crisis saw major currencies quickly collapse. (Source:&nbsp;<a href="https://substack.com/redirect/48d241f2-f332-40a5-ad4c-7ebb39d30b2b?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" rel="noreferrer noopener" target="_blank">FRED</a>)</figcaption></figure>
I don't have many memories from the Dot-com Bubble bursting. Back then, I had little interest in or exposure to the stock market, and neither did the people around me. But I do remember watching 9/11 live on TV in my dorm with my roommates at Boston University. I remember not being able to get a hold of family members in New York and Kentucky because the phones were overloaded. I remember the extreme range of reactions from my friends: some fled Boston out of fear; some used it as an excuse to skip some classes; some explored joining the armed forces. Everyone was rattled. Everyone felt less safe.
And for my college friends and I, it soon became clear that we would all be entering a tighter job market with an elevated unemployment rate. Things weren't great.
<figure class="wp-block-image"><a href="https://substack.com/redirect/3012d5c1-016c-4c41-bd92-903bc05ed66d?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" target="_blank" rel="noreferrer noopener"><img decoding="async" src="https://ci3.googleusercontent.com/meips/ADKq_Nb0sOgwPLHdgVjD8GPkACVilOFgV79U6eM4TgYfAGwnctzGbMR6ckGKGaMPPJmsb335K_PFhJz4WzItHVGkc-bciz_-F14_LohPnz1e2HpiOm2QhOBOd-J9EIHnekR9fLA1aNgN6uRaT1X3WbGbRx5DOGupi9ZDHNneKuAvXZGEmDVM3ReFQZBcUyY2f1H-Ay1mbnYPx4VYbn3W5AJiz5f6hjLhCVp-ffWkATcoPZI6z76v5VgSvSyrABDdTIpl0jEQnJHTd9V9EnXbPaFFJYucwOVhTrusQsdzlUGKQhL8qv42U2AvlkHz=s0-d-e1-ft#https://substackcdn.com/image/fetch/w_1100,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F5a352b63-7540-4ce3-8c89-537c29545c92_939x465.png" alt="" /></a><figcaption class="wp-element-caption">The economy looked great when I entered college in 2000. It wasn't as great when I graduated in 2004. (Source:&nbsp;<a href="https://substack.com/redirect/489aeeec-4d13-46b3-9414-adcfd9c83d5a?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" rel="noreferrer noopener" target="_blank">FRED</a>)</figcaption></figure>
After graduating from college in 2004 and after months of searching, I randomly got a job as a contract paralegal where I got my first serious introduction to equity research. I quickly became hooked on learning about the what made the stock market move.&nbsp;<a href="https://substack.com/redirect/1b7f3cf6-9b8c-48b8-9e8c-657e8bb35809?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" rel="noreferrer noopener" target="_blank">In 2006</a>, I got a job at Forbes Newsletters researching and writing up stock picks. I also enrolled in the CFA program that year, which helped me develop a sophisticated understanding of things like mortgage backed securities, collateralized debt obligations, derivatives, and value-at-risk models.
This education super-charged my fear and my feeling of hopelessness as the world tipped into recession in 2007 and spiraled into Global Financial Crisis (GFC) in 2008. The more I understood, the more I felt like there was no way out of it. And many pundits seemed to agree. I remember respected financial market prognosticators going on TV and proclaiming that the government's bailouts of the big banks, the automakers, and the GSEs were proof that it was "the end of capitalism."
<figure class="wp-block-image"><a href="https://substack.com/redirect/066cd371-b8d8-4648-b40b-879d376f5e68?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" target="_blank" rel="noreferrer noopener"><img decoding="async" src="https://ci3.googleusercontent.com/meips/ADKq_NaHljZ6b-KoD6nT2WIv6xYdXPocFXWXu4HDJUY33P7BLHHUuuQ_fNcef2S4ee27E-mWgEAGeIAKHuTZutEw925FgEKQoJcsGaOFNx6uuhwUGHB80PHQmc79NaMeJi3P31c6CoqomzQ6O1nLY4H8AdfuHkSGpMw4-9ngz9pxbETBVMF83_jAQVwa8a-1W72rxOjozDed21eOENit9woECSpcIIkP4vX2JbKzhtQ4WKfAI00mG0nvj4CV2oSNoTAIDh-X74mBJC3__f0xwQ0KVRCGdfG7tHc03FeMW7gctrD4InpzQ2dt3rtJww=s0-d-e1-ft#https://substackcdn.com/image/fetch/w_1100,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F0396d240-eb39-492f-925c-2a8f3825df94_1472x834.png" alt="" /></a><figcaption class="wp-element-caption">The S&amp;P 500 fell 57% from its Oct 2007 high of 1,565 to its March 2009 low of 666. (Source: Yahoo Finance)</figcaption></figure>
It wasn't the end of capitalism, though many were convinced the housing market would never come back as we entered a "<a href="https://substack.com/redirect/68d9f88d-7fd8-4862-8ff9-e7c83cc7921b?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" rel="noreferrer noopener" target="_blank">new normal</a>" of slow growth. Another popular phrase in the wake of the crisis was "<a href="https://substack.com/redirect/6cb20fca-d357-4cd6-b289-bee51a7d8229?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" rel="noreferrer noopener" target="_blank">secular stagnation</a>." Admittedly, I was sold on the idea that economic growth would forever be a long slog. You can't blame me. In 2010,&nbsp;<a href="https://substack.com/redirect/1b7f3cf6-9b8c-48b8-9e8c-657e8bb35809?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" rel="noreferrer noopener" target="_blank">I got laid off from my job</a>&nbsp;and I re-entered a job market flooded with unemployed people with backgrounds in finance.
But the post-GFC recovery helped me appreciate the resilience of the consumers and businesses propelling the economy forward. I got a great job in 2011, and over the next decade my income soared. Those years were riddled with numerous macro hiccups, but nothing could keep the economy and the stock market from accelerating again and blasting through record highs.
And then came the COVID-19 pandemic.
Those first 6-9 months were surreal. I remember feeling like I was living a sci-fi horror film. At many points I thought this new strange way of life would be permanent. Meanwhile, I was constantly worried that the whole economy would collapse on itself.
<figure class="wp-block-image"><a href="https://substack.com/redirect/0688f86e-f536-4b28-9774-f75e1a04a46d?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" target="_blank" rel="noreferrer noopener"><img decoding="async" src="https://ci3.googleusercontent.com/meips/ADKq_NbscFUtA6IwDvX5NqUG8Nn6t2luLEGjO3a3XB7MX6TCBprlzYQZAJM_uHvLxP7d4AJfLNYHRefSH_Er7I17FlRvRBHpeA6mhHqGCiHh3K-hpEduxkBNNBG19fTTnzyjVgV-XtvjCtlxH7qRsNMXrmtm-S6Zuoaoz4Fvk5k4rmmt_Bd_qMXqQHQFOT1DjsPAagFkDv1f1k3ZIbW_5cmkt03dS8AkuhXxL6DS6WThOZ9DJ-5nvGEcB9samE1oWNv7I3WHxqfxDhFqE79XUQJDokhNycPZtfhhztb7jEfa2lpps4m6iBhRokrN=s0-d-e1-ft#https://substackcdn.com/image/fetch/w_1100,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9c91b707-de5d-4221-ade3-af302a81b88a_939x465.png" alt="" /></a><figcaption class="wp-element-caption">COVID-19 caused the economy to nearly screech to a halt. (Source:&nbsp;<a href="https://substack.com/redirect/489aeeec-4d13-46b3-9414-adcfd9c83d5a?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" rel="noreferrer noopener" target="_blank">FRED</a>)</figcaption></figure>
The discovery of the vaccine certainly helped things turn around. Fast forward a few years, and most things in the economy are back to normal. Notably,&nbsp;<a href="https://substack.com/redirect/89de024a-89ed-401a-804f-8b1d28d3b361?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" rel="noreferrer noopener" target="_blank">cruise</a>&nbsp;and&nbsp;<a href="https://substack.com/redirect/fd044ff2-d85d-449e-898a-e92b554d80ba?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" rel="noreferrer noopener" target="_blank">air travel</a>&nbsp;have more than recovered as most people have gotten comfortable again with being in tight spaces with strangers —&nbsp;<a href="https://substack.com/redirect/ca970b27-04e4-4579-8604-6191fa0425a7?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" rel="noreferrer noopener" target="_blank">unless it's in an office for work</a>.
So despite the pain, the trauma, and even the loss of life, all these experiences eventually confirmed that we'll always bounce back.
<h2 class="wp-block-heading">People will always want things to be better &#x1f4c8;</h2>
The economy and the stock market have&nbsp;<a href="https://substack.com/redirect/0ac3db5d-094a-4e05-8ba2-568c104debf2?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" rel="noreferrer noopener" target="_blank">always had</a>&nbsp;an upward bias.
This makes sense&nbsp;<a href="https://substack.com/redirect/421fc3e1-659f-4eee-8449-f3ccc06c20d5?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" rel="noreferrer noopener" target="_blank">if you think about it</a>. There are way more people who want things to be better, not worse. And that demand incentivizes entrepreneurs and businesses to supply better goods and services. The winners in this process get bigger as revenue grows. Some even get big enough to get listed in the stock market. As revenue grows,&nbsp;<a href="https://substack.com/redirect/edda2a69-5be1-43a1-8786-99ad82579e8f?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" rel="noreferrer noopener" target="_blank">so do earnings</a>. And earnings drive stock prices.
I can't imagine anything changing these attitudes. Sure, there will be periods of when we feel angry and hopeless along the way. But we're never gonna wake up one day and decide we have everything we want or settle on the idea that what we've got can't be improved on.
And there will always be a sense of urgency. Even during difficult periods, people understand that life won't wait. You're getting older. You're kids are getting older. You're parents are getting older. If you have the resources,&nbsp;<a href="https://substack.com/redirect/cdba9ccf-e431-4691-add0-603ee3b2cd5f?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" rel="noreferrer noopener" target="_blank">you won't put your lives on hold</a>. This is bullish as it keeps the wheels on the economy spinning.
Sure, many things change after all the events I mentioned. But things are always changing. Importantly, the changes that stuck have never prevent the economy and the markets from setting new records.
<h2 class="wp-block-heading">Where we are today</h2>
If you've been following the news at all over the past two months, you've probably heard at least a few folks talking about how the Trump administration's approach to trade policy is damaging the U.S.'s standing in the world while also threatening to send the global economy into recession.
As the stock market tumbled, phrases like "<a href="https://substack.com/redirect/01ee3155-4eb4-40a5-8f63-26b5ac1895a4?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" rel="noreferrer noopener" target="_blank">sell America</a>" and "<a href="https://substack.com/redirect/c8b83f7d-203d-4e29-bae4-6879cb4e671c?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" rel="noreferrer noopener" target="_blank">end of American exceptionalism</a>" began to trend.&nbsp;<a href="https://substack.com/redirect/0e3bfd9a-aef4-447f-a3b3-5dc39ab36d0a?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" rel="noreferrer noopener" target="_blank">Popular measures of investor sentiment</a>&nbsp;tanked.
<figure class="wp-block-image"><a href="https://substack.com/redirect/6a7ef8a2-1216-4073-a921-adb64c11fe1e?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" target="_blank" rel="noreferrer noopener"><img decoding="async" src="https://ci3.googleusercontent.com/meips/ADKq_NaY2UYtD_m_cCbiQrz03XzG6_fndw5nNrVMqzc_hzDYFLqXa7gZhAx_yg__5Pb3HA0i1-i8n4JGx7uNsuDwwfxT1PgQODmLHJYt7d-3jt8UJnq96h3Yid8wZhZJXPSpM4TtVBZ0qeu5sC5A7oPRLxt1AVcDZ1HVYXga1EDrhXxpy3k1lZCp_CcPtbiHF5pf2K_XDPm1hIFUSmbTLNgXM2rnYNIgyiDZ7Tm8nPJqAEs3_7z8RcN8jelSZDuFy9K2l7TkYMQ_EsrdJOdjvD9EQbq-jSzcvL02-f2H9vqhfQ1e2S0sOXJ-Mqt-Dw=s0-d-e1-ft#https://substackcdn.com/image/fetch/w_1100,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F412304bb-608f-4ee0-b9a4-76f38a1a9f03_1972x842.png" alt="" /></a><figcaption class="wp-element-caption">Barron's Big Money poll revealed historic levels of bearishness. (Source:&nbsp;<a href="https://substack.com/redirect/52ba27cc-a783-4128-a30d-b6f0e285e87c?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" rel="noreferrer noopener" target="_blank">Barron's</a>)</figcaption></figure>
To be clear, I think the past two months created some damage, and we have yet to learn the extent of that damage. It's certainly possible that we're in a recession or headed for one. And it's certainly possible the stock market could take another leg lower.
But I'm nowhere near convinced that we're destined for a extended, multi-year period of turmoil and pain.
Our system is amazing at self-correcting. Whether it's through votes or something else, we always seem to find a way to get things back on track toward increasing prosperity and improving our standard of living.
And to repeat&nbsp;<a href="https://substack.com/redirect/29c413c7-c5cd-4845-b921-67ca23a9ede1?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" rel="noreferrer noopener" target="_blank">what I said last week</a>: There's basically three scenarios investors always have to consider: 1) Things improve from here, and the market goes up; 2) Things get worse before they get better, which means markets could fall before resuming a more firm rally; or 3) Things get worse and never get better.
If we're facing scenario 3, then we may have bigger problems than stocks not recovering. But scenario 3 has&nbsp;<a href="https://substack.com/redirect/84055449-e2e7-434a-9e0d-ab334afbeef6?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" rel="noreferrer noopener" target="_blank">never played out</a>.
Scenarios 1 and 2 favor long-term investors. Maybe things get worse before they get better. (Note:&nbsp;<a href="https://substack.com/redirect/f1a11344-054b-4ae9-b89d-52cc5dd2c420?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" rel="noreferrer noopener" target="_blank">Timing market</a>&nbsp;bottoms is&nbsp;<a href="https://substack.com/redirect/e0630f35-18e4-4bdd-a1db-86faac336c59?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" rel="noreferrer noopener" target="_blank">nearly impossible</a>.) But staying long the stock market covers you in case the low of this cycle is behind us.
I'll leave you with Warren Buffett said earlier this month at&nbsp;<a href="https://substack.com/redirect/19bde3b3-6107-4aae-b826-8c47b51bd5d2?j=eyJ1Ijoid252OGYifQ.jVQb6opeiKhMTzCAB2x0eMpa3LqEuHgwpXD1DeTk7x0" rel="noreferrer noopener" target="_blank">Berkshire Hathaway's annual meeting</a>:
<blockquote class="wp-block-quote is-layout-flow wp-block-quote-is-layout-flow">"We're always in the process of change. We'll always find all kinds of things to criticize in the country. …&nbsp;If you don't think the United States has changed since I was born in 1930… We've gone through all kinds of things. We've gone through great recessions. We've gone through world wars. We've gone through the development of the atomic bomb that we never dreamt of when I was born. So I would not get discouraged about the fact that it doesn't look like we've solved every problem that's come along."
</blockquote>
The 94-year-old investor has lived through everything, and he's made a fortune investing in the stock market along the way.
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Remembering Moments When I Thought Things Took A Permanent Turn For The Worse

<a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.institutionalpropertyadvisors.com%2F&amp;esheet=54257117&amp;newsitemid=20250519504201&amp;lan=en-US&amp;anchor=Institutional+Property+Advisors+%28IPA%29&amp;index=1&amp;md5=e2951cec00b67290040dd5c556531169">Institutional Property Advisors (IPA)</a>, a division of <a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.marcusmillichap.com%2F&amp;esheet=54257117&amp;newsitemid=20250519504201&amp;lan=en-US&amp;anchor=Marcus+%26amp%3B+Millichap+%28NYSE%3AMMI%29&amp;index=2&amp;md5=368a3f4e5f5cb1c099725e50b0f4cf77">Marcus &amp; Millichap (NYSE:</a><a href="https://www.benzinga.com/stock/MMI#NYSE">MMI</a>) dedicated to serving the company's institutional clients, announced today the sale of Zaterra, a 392-unit multifamily property in Chandler, Arizona. The asset traded for $137.5 million, or $350,765 per unit.

Marcus & Millichap's Institutional Property Advisors Announces Sale Of Zaterra For $137.5M

Piper Sandler analyst Charles Neivert upgrades Methanex (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MEOH#NASDAQ">MEOH</a>) from Neutral to Overweight and raises the price target from $36 to $48.

MEOH

Piper Sandler Upgrades Methanex to Overweight, Raises Price Target to $48

U.S. stocks trimmed early-session losses by midday Monday, as investors showed limited concern after Moody's downgraded U.S. sovereign credit from Aaa to Aa1, effectively stripping the world's largest economy of its last <a href="https://www.benzinga.com/25/05/45492889/americas-credit-strength-just-got-cut-again-should-you-panic">top-tier credit rating. </a>
The S&amp;P 500 index hovered near Friday's close. A green end to the session would mark the sixth consecutive daily gain. The Nasdaq 100 also traded flat, while the Dow Jones Industrial Average outperformed, and small caps lagged. 
Bond markets initially reacted sharply, with 30-year Treasury yields spiking above 5% following the downgrade. Yet, buying interest emerged during the session, pulling yields back to 4.95%. The iShares 20+ Year Treasury Bond ETF (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/TLT#NASDAQ">TLT</a>) still was down 0.6% on the day. 
The U.S. dollar index (DXY) weakened 0.6% to 100.40, reflecting moderate selling pressure on the greenback. Sector performance was muted overall, except for energy, which fell 1.5%. Crude oil slipped 0.4%, while natural gas dropped 6% amid oversupply concerns. 
Gold rose 1% to $3,235 per ounce, supported by safe-haven flows. Bitcoin (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/btc/usd">BTC</a>) rallied 2%, climbing above the $105,000 mark.
<h3 class="wp-block-heading">Monday&#8217;s Performance In Major US Indices, ETFs</h3>
<figure class="wp-block-table is-style-stripes"> 
<table class="has-fixed-layout">
<tbody>
<tr>
<td>Major Indices</td>
<td>Price</td>
<td>1-day %chg</td>
</tr>
<tr>
<td>Dow Jones</td>
<td>42,824.92</td>
<td>0.4%</td>
</tr>
<tr>
<td>Nasdaq 100</td>
<td>21,456.60</td>
<td>0.1 %</td>
</tr>
<tr>
<td>S&amp;P 500</td>
<td>5,965.78</td>
<td>0.1 %</td>
</tr>
<tr>
<td>Russell 2000</td>
<td>2,102.02</td>
<td>-0.5%</td>
</tr>
</tbody>
</table>
<figcaption class="wp-element-caption">Updated by 1:05 p.m. ET</figcaption></figure>
<ul class="wp-block-list">
<li><a href="https://www.benzinga.com/analyst-ratings/analyst-color/25/05/45497403/is-the-dollars-global-reserve-role-at-risk-after-moodys-downgrade">Is The Dollar&#8217;s Global Reserve Role At Risk After Moody&#8217;s Downgrade?</a></li>
</ul>
According to&nbsp;<a href="https://www.benzinga.com/pro/?utm_source=BZprocontent&amp;t=be2bearmibe3na1">Benzinga Pro</a>&nbsp;data:
<ul class="wp-block-list">
<li>The&nbsp;SPDR S&amp;P 500 ETF Trust (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/SPY#NYSE">SPY</a>) inched 0.1% up to $594.91.</li>
<li>The&nbsp;SPDR Dow Jones Industrial Average&nbsp;(NYSE:<a class="ticker" href="https://www.benzinga.com/stock/DIA#NYSE">DIA</a>) rose 0.4% to $428.18.</li>
<li>The tech-heavy&nbsp;Invesco QQQ Trust Series&nbsp;(NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/QQQ#NASDAQ">QQQ</a>)&nbsp;edged 0.1% higher to $522.01.</li>
<li>The&nbsp;iShares Russell 2000 ETF (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/IWM#NYSE">IWM</a>) fell 0.5% to $208.80.</li>
<li>The&nbsp;Health Care&nbsp;Select Sector SPDR Fund (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/XLV#NYSE">XLV</a>) outperformed, up 0.7%; the&nbsp;Energy&nbsp;Select Sector SPDR Fund&nbsp;(NYSE:<a class="ticker" href="https://www.benzinga.com/stock/XLE#NYSE">XLE</a>) lagged, down 1.5%.</li>
</ul>
<h3 class="wp-block-heading">Monday&#8217;s Stock Movers</h3>
<ul class="wp-block-list">
<li>UnitedHealth Group Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/UNH#NYSE">UNH</a>) jumped 8%, extending Friday's 6% surge, after several company executives bought shares <a href="https://www.benzinga.com/25/05/45493652/700m-asset-manager-exits-unitedhealth-stock-says-medicare-advantage-is-facing-a-perfect-storm">during the recent selloff</a>.</li>
<li>New Fortress Energy Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NFE#NASDAQ">NFE</a>) rallied 21%, following a nearly 60% decline last week amid lower-than-expected earnings. </li>
<li>Novavax Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NVAX#NASDAQ">NVAX</a>) surged 18% after the FDA approved its Nuvaxovid COVID-19 vaccine <a href="https://www.benzinga.com/government/regulations/25/05/45488265/novavax-wins-limited-fda-nod-for-covid-shot-cleared-only-for-seniors-high-risk-groups-amid-safety-scrutiny">for high-risk individuals</a>, including seniors over 65 and those aged 12–64 with underlying health conditions. Shares of Moderna Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MRNA#NASDAQ">MRNA</a>) rose 6.4%.</li>
</ul>
Now Read: 
<ul class="wp-block-list">
<li><a href="https://www.benzinga.com/analyst-ratings/analyst-color/25/05/45497403/is-the-dollars-global-reserve-role-at-risk-after-moodys-downgrade">Is The Dollar&#8217;s Global Reserve Role At Risk After Moody&#8217;s Downgrade?</a></li>
</ul>
Image: Shutterstock

Macro Economic Events

Sector ETFs

Bonds

Broad U.S. Equity ETFs

Treasuries

Econ #s

Tech

ETFs

$BTC

SPDR Dow Jones Industrial Average ETF Trust

MRNA

NVAX

iShares Trust Barclays 20+ Year Treasury Bond Fund

Select Sector SPDR-Consumer Discretionary

Stocks Mixed, Treasury Bonds Slip On Moody's US Downgrade: What's Driving Markets Monday?

Globant S.A. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/GLOB#NYSE">GLOB</a>) reported worse-than-expected first-quarter financial results, issued second-quarter guidance below estimates, and cut its FY25 guidance, after the closing <a href="https://www.benzinga.com/quote/GLOB/earnings">bell on Thursday</a>.
Globant reported quarterly earnings of $1.50 per share which missed the analyst consensus estimate of $1.58 per share. The company reported quarterly sales of $611.09 million which missed the analyst consensus estimate of $621.38 million.
&#8220;Globant&#8217;s spirit of building and reinvention is stronger than ever. We are largely focused on AI-related opportunities, and assisting our clients in transforming their respective businesses and leveraging technology to drive growth and competitive advantages. Our comprehensive growth strategy unites our 100-squared client-centric vision with our industry-specialized AI Studios and subscription model. This strategy is powered by our AI Pods and the Globant Enterprise AI platform, which we believe positions Globant as the only player in the industry with such a comprehensive offering. With a robust pipeline and expected sequential growth for Q2, we are not just navigating the future; as builders, we are actively creating it, reaffirming our commitment to lead the next wave of technological transformation,&#8221; said Martín Migoya, Globant&#8217;s CEO and co-founder.
Globant shares gained 3.1% to trade at $104.67 on Monday.
These analysts made changes to their price targets on Globant following earnings announcement.
<ul class="wp-block-list">
<li>Goldman Sachs analyst James Schneider maintained Globant with a Neutral and lowered the price target from $225 to $120.</li>
<li>Mizuho analyst Dan Dolev maintained the stock with an Outperform rating and lowered the price target from $194 to $153.</li>
</ul>
Considering buying GLOB stock? Here&#8217;s what analysts think: 
<figure class="wp-block-image size-large is-resized"><img loading="lazy" decoding="async" width="1024" height="562" src="https://editorial-assets.benzinga.com/wp-content/uploads/2025/05/19134451/image-232-1024x562.png" alt="" class="wp-image-920178" style="width:628px;height:auto" srcset="https://editorial-assets.benzinga.com/wp-content/uploads/2025/05/19134451/image-232-1024x562.png 1024w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/05/19134451/image-232-300x165.png 300w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/05/19134451/image-232-768x422.png 768w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/05/19134451/image-232.png 1102w" sizes="(max-width: 1024px) 100vw, 1024px" /></figure>
Read This Next:
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<li> <a href="https://www.benzinga.com/analyst-ratings/price-target/25/05/45490061/5-stock-picks-last-week-from-wall-streets-most-accurate-analysts-6">5 Stock Picks Last Week From Wall Street&#8217;s Most Accurate Analysts</a> </li>
</ul>
Photo via Shutterstock

Earnings

Trading Ideas

GLOB

Globant Analysts Slash Their Forecasts After Q1 Results

Northland Capital Markets analyst Jeff Grampp initiates coverage on Hallador Energy (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/HNRG#NASDAQ">HNRG</a>) with a Outperform rating and announces Price Target of $23.

Initiation

HNRG

Northland Capital Markets Initiates Coverage On Hallador Energy with Outperform Rating, Announces Price Target of $23

Semler Scientific Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SMLR#NASDAQ">SMLR</a>) shares are seeing increased attention to start the week after the company announced a new board appointment that&#8217;s causing a spike in chatter on <a href="https://www.benzinga.com/topic/social-media">various social platforms</a>.
What To Know: Semler Scientific, a technology company that has adopted a Bitcoin (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/btc/usd">BTC</a>) treasury strategy, on Monday announced that it <a href="https://www.benzinga.com/pressreleases/25/05/n45490896/semler-scientific-appoints-natalie-brunell-to-its-board-of-directors">appointed</a> crypto journalist and podcast host&nbsp;Natalie Brunell&nbsp;to its board of directors.
Brunell is an influential crypto educator and hosts a popular Bitcoin podcast called &#8220;Coin Stories.&#8221; The company on Monday said that its latest board addition reflects its continued commitment to its Bitcoin treasury strategy. 
&#8220;Natalie is a highly respected journalist and educator – and a leading advocate for&nbsp;Bitcoin, with a deep understanding of its role as a transformative asset. As the 4th&nbsp;largest U.S. public company on the&nbsp;Bitcoin&nbsp;Standard in terms of&nbsp;Bitcoin&nbsp;holdings, we believe we are a strategic asset. Her insights will be instrumental as we pursue our&nbsp;Bitcoin&nbsp;treasury strategy and aim to deliver long-term value to our stockholders,&#8221; said Eric Semler, chairman of Semler Scientific.
Semler is seeing increased attention on multiple social platforms, especially on X, where the company is being talked about in comparison to Strategy Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MSTR#NASDAQ">MSTR</a>). 
Strategy&#8217;s Michael Saylor <a href="https://x.com/saylor/status/1924440559634076050">congratulated</a> the Semler team on X in response to a post from the company&#8217;s chairman. He also <a href="https://x.com/saylor/status/1924444076192981375">responded</a> to a post from Brunell announcing the new appointment. 
In&nbsp;May 2024, Semler Scientific became the second publicly traded company in the U.S. to adopt a&nbsp;Bitcoin&nbsp;treasury strategy, which involves using proceeds from equity and debt financings, as well as cash flows from operations, to strategically accumulate&nbsp;Bitcoin.
Semler reported first-quarter financial results last week, reporting Bitcoin treasury highlights similar to Strategy. The company said it achieved a &#8220;BTC Yield&#8221; of 21.9% in the first quarter and reported a &#8220;BTC Gain&#8221; of 7.1 in the first quarter and 510.3 year-to-date. The company said it held a total of 3,192 Bitcoin as of March 31. 
SMLR Price Action: <a href="http://benzinga.com/quote/SMLR">Semler Scientific shares</a> were up 7.84% at $44.08 at the time of publication Monday, according to Benzinga Pro. The company&#8217;s stock is down approximately 18% year-to-date, but has risen 88% over a one-year period on the back of its Bitcoin treasury strategy announcement.
Photo: Yalcin Sonat/Shutterstock.

Movers

MSTR

SMLR

Bitcoin-Linked Semler Scientific Stock Is Trending On Monday: What's Going On?

Mizuho analyst Mara Goldstein maintains Kura Oncology (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/KURA#NASDAQ">KURA</a>) with a Outperform and lowers the price target from $32 to $30.

KURA

Mizuho Maintains Outperform on Kura Oncology, Lowers Price Target to $30

Mizuho analyst Vijay Rakesh maintains Super Micro Computer (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SMCI#NASDAQ">SMCI</a>) with a Neutral and raises the price target from $32 to $40.

SMCI

Mizuho Maintains Neutral on Super Micro Computer, Raises Price Target to $40

TD Securities analyst Ryan Langston downgrades UnitedHealth Group (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/UNH#NYSE">UNH</a>) from Buy to Hold and lowers the price target from $520 to $308.

Downgrades

TD Securities Downgrades UnitedHealth Group to Hold, Lowers Price Target to $308

Fed's Kashkari Says Coming Into This Year Economic Conditions Were Good; Says There's Big Uncertainty Now In The Economy; Says Doesn't Know When Tariff Landscape Will Settle Out; Says Businesses Are Holding Off On Investment Amid Uncertainty

Mizuho analyst Vijay Rakesh maintains Dell Technologies (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/DELL#NYSE">DELL</a>) with a Outperform and raises the price target from $140 to $145.

DELL

Mizuho Maintains Outperform on Dell Technologies, Raises Price Target to $145

Mizuho analyst Vijay Rakesh maintains Advanced Micro Devices (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AMD#NASDAQ">AMD</a>) with a Outperform and raises the price target from $117 to $135.

Mizuho Maintains Outperform on Advanced Micro Devices, Raises Price Target to $135

<a href="https://truthsocial.com/@realDonaldTrump/114535693441367601">https://truthsocial.com/@realDonaldTrump/114535693441367601</a>

President Trump Says Ukraine Can Benefit From Trade; Says Negotiations Will Begin Immediately;Says Vatican Says It Would Be Interested In Hosting Russia-Ukraine Talks

U.S. stocks traded higher midway through trading, with the Dow Jones index gaining more than 150 points on Monday.
The Dow traded up 0.40% to 42,825.71 while the NASDAQ rose 0.02% to 19,215.06. The S&amp;P 500 also rose, gaining, 0.13% to 5,965.84.
Check This Out: <a href="https://www.benzinga.com/25/05/45489465/top-3-tech-and-telecom-stocks-that-may-rocket-higher-this-month">Top 3 Tech And Telecom Stocks That May Rocket Higher This Month</a>
Leading and Lagging Sectors Consumer staples shares rose by 0.1% on Monday.
In trading on Monday, energy stocks dipped by 1.5%.
Top Headline
Global Ship Lease, Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/GSL#NYSE">GSL</a>) reported upbeat results for the first quarter on Monday.
The company posted quarterly earnings of $2.65 per share which beat the analyst consensus estimate of $2.31 per share. The company reported quarterly sales of $190.97 million which beat the analyst consensus estimate of $175.23 million.
Equities Trading UP &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<ul class="wp-block-list">
<li>DigiAsia Corp. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/FAAS#NASDAQ">FAAS</a>) shares shot up 188% to $0.5351 after the company announced the launch of Bitcoin treasury reserve strategy. The company said it is exploring up to $100 million capital raise to acquire Bitcoin.</li>
<li>Shares of Protagenic Therapeutics, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/PTIX#NASDAQ">PTIX</a>) got a boost, surging 163% to $7.96 after the company entered a business combination with Phytanix</li>
<li>Novavax, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NVAX#NASDAQ">NVAX</a>) shares were also up, gaining 8% to $7.29 after the company provided FY25, 2026, and 2027 R&amp;D and SG&amp;A expense guidance. The FDA gave its conditional approval to its COVID-19 vaccine, targeting specific populations under particular conditions.</li>
</ul>
Equities Trading DOWN
<ul class="wp-block-list">
<li>Gilat Satellite Networks Ltd. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/GILT#NASDAQ">GILT</a>) shares dropped 9% to $6.08 after the company reported a first-quarter revenue miss.</li>
<li>Shares of Quantum Computing Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/QUBT#NASDAQ">QUBT</a>) were down 10% to $11.64. Quantum Computing, last week, reported better-than-expected first-quarter EPS results.</li>
<li>Archer Aviation Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/ACHR#NYSE">ACHR</a>) was down, falling 10% to $12.01.</li>
</ul>
Commodities In commodity news, oil traded up 0.1% to $62.51 while gold traded up 1.4% at $3,233.
Silver traded up 0.2% to $32.410 on Monday, while copper rose 1% to $4.6390.
Euro zone
European shares were mixed today. The eurozone's STOXX 600 fell 0.20%, while Spain's IBEX 35 Index rose 0.06%. London's FTSE 100 fell 0.14%, Germany's DAX 40 gained 0.28% and France's CAC 40 slipped 0.30% during the session.
Asia Pacific Markets
Asian markets closed mostly lower on Monday, with Japan's Nikkei falling 0.68%, Hong Kong's Hang Seng Index declining 0.05%, China's Shanghai Composite Index falling 0.004% and India's BSE Sensex declining 0.33%.
Economics
The CB Leading Index fell 1% month-over-month in April.
Now Read This: 
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</ul>
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