Syndax Pharmaceuticals 株価情報 (NASDAQ: SNDX)

最新ニュース Syndax Pharmaceuticals (NASDAQ:SNDX) 株価情報

SYNDAX PHARMACEUTICALS INC

Syndax Pharmaceuticals

Syndax Pharmaceuticals Inc is a clinical-stage biopharmaceutical company focused on developing a pipeline of combination therapies in multiple cancer indications. Its product candidates include revumenib and axatilimab. It is developing revumenib, a selective menin-MLL inhibitor for KMT2A-rearranged (MLL-r) and NPM1-mutant acute leukemias, including ALL and AML. It is also developing axatilimab, a CSF-1R-blocking antibody for cGVHD and idiopathic pulmonary fibrosis. Entinostat is its oral, small molecule product candidate that has direct effects on both cancer cells and immune regulatory cells. The business activity of the group is functioned through the region of the United States.

Syndax Pharmaceuticals, Inc. - Common Stock

Syndax Pharmaceuticals Inc

U.S. stocks were lower, with the Nasdaq Composite falling more than 50 points on Tuesday.
Shares of Agilysys, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AGYS#NASDAQ">AGYS</a>) rose sharply during Tuesday's session following <a href="https://in.benzinga.com/news/earnings/25/05/45506384/agilysys-reports-better-than-expected-q4-earnings-shares-move-higher-after-hours">better-than-expected fourth-quarter results.</a>
Agilysys reported fourth-quarter revenue of $74.27 million, beating analyst estimates of $71.42 million, according to Benzinga Pro. The hospitality software provider reported fourth-quarter earnings of 54 cents per share, beating estimates of 29 cents per share.
Agilysys shares jumped 18.6% to $98.50 on Tuesday.
Here are some other big stocks recording gains in today&#8217;s session.
<ul class="wp-block-list">
<li>D-Wave Quantum Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/QBTS#NYSE">QBTS</a>) shares jumped 26% to $16.59 after the company announced it launched its Advantage2 quantum system to address problems in optimization, AI, and materials simulation.</li>
<li>Mind Medicine (MindMed) Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MNMD#NASDAQ">MNMD</a>) shares rose 17.1% to $8.21. MindMed announced new employee inducement grants.</li>
<li>Amer Sports, Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/AS#NYSE">AS</a>) jumped 16.6% to $36.62 after the company reported better-than-expected first-quarter financial results and raised its FY25 guidance.</li>
<li>X Financial (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/XYF#NYSE">XYF</a>) gained 15.8% to $17.38 after the company reported a year-over-year increase in first-quarter financial results.</li>
<li>COMPASS Pathways plc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CMPS#NASDAQ">CMPS</a>) rose 14.9% to $4.9999.</li>
<li>Syndax Pharmaceuticals, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SNDX#NASDAQ">SNDX</a>) gained 11% to $10.32.</li>
<li>GIBO Holdings Limited (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/GIBO#NASDAQ">GIBO</a>) rose 10.4% to $3.50.</li>
<li>Regencell Bioscience Holdings Limited (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/RGC#NASDAQ">RGC</a>) gained 9.6% to $385.35.</li>
<li>Sasol Limited (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/SSL#NYSE">SSL</a>) rose 8.5% to $4.45.</li>
<li>Sibanye Stillwater Limited (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/SBSW#NYSE">SBSW</a>) gained 8.5% to $5.26.</li>
<li>Magnite, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MGNI#NASDAQ">MGNI</a>) shares rose 6.3% to $16.29. Amazon Publisher Services (APS) and Magnite announced a deeper streaming TV collaboration through APS&#8217; Transparent Ad Marketplace (TAM) and Magnite&#8217;s SpringServe.</li>
<li>Pegasystems Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/PEGA#NASDAQ">PEGA</a>) gained 5.3% to $103.64 following announcements that the company will join the S&amp;P Midcap 400. </li>
</ul>
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</ul>
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News

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Trading Ideas

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Agilysys, Amer Sports, X Financial And Other Big Stocks Moving Higher On Tuesday

– Revumenib abstracts highlight compelling results in acute leukemia across the frontline and R/R setting and multiple genetic populations, including mNPM1, KMT2Ar, and NUP98r –
– Axatilimab abstracts highlight the robust responses observed in different organs and subgroups of patients with chronic GVHD in the AGAVE-201 trial –
NEW YORK, May 14, 2025 (GLOBE NEWSWIRE) -- Syndax Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SNDX#NASDAQ">SNDX</a>), a commercial-stage biopharmaceutical company advancing innovative cancer therapies, today announced that multiple abstracts showcasing clinical data for Revuforj&#xAE; (revumenib) and Niktimvo&#x2122; (axatilimab-csfr) were accepted for presentation at the 30th European Hematology Association (EHA) Annual Congress Meeting being held June 12-15, 2025, in Milan, Italy.

Syndax Pharma: Multiple Abstracts Showcasing Clinical Data For Revuforj Accepted For Presentation At EHA Annual Congress Meeting

– Revumenib abstracts highlight compelling results in acute leukemia across the frontline and R/R setting and multiple genetic populations, including mNPM1, KMT2Ar, and NUP98r –
– Axatilimab abstracts highlight the robust responses observed in different organs and subgroups of patients with chronic GVHD in the AGAVE-201 trial –

Biotech

Events

General

Syndax Presents Data Showcasing Revuforj And Niktimvo At EHA 2025

– Primary endpoint met in R/R mNPM1 AML patients in pivotal Phase 2 portion of the AUGMENT-101 trial –
– Robust remission rates in heavily pre-treated R/R mNPM1 AML population with nearly 50% overall response rate –
– sNDA for revumenib in R/R mNPM1 AML submitted in April 2025 –
NEW YORK, May 07, 2025 (GLOBE NEWSWIRE) -- Syndax Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SNDX#NASDAQ">SNDX</a>), a commercial-stage biopharmaceutical company advancing innovative cancer therapies, today announced that data from the pivotal Phase 2 portion of the AUGMENT-101 trial of revumenib, a first-in-class menin inhibitor, in patients with relapsed or refractory (R/R) mutant NPM1 (mNPM1) acute myeloid leukemia (AML) have been <a href="https://www.globenewswire.com/Tracker?data=HgKy5C2YZkNevu3gvMKYfT9ddafykYDpCX9nwMwmfCE52FG-kbtj3b2qYfKbkQLUG9XZJAGU6wnWCP5L04VKOPOm0OV5rWzQrIRHJ4Z21lGDVI0tIrpWCsYoyn3Dc919DUnel0CkQovP3-3HDaUq3klmCmvgvQRHUupU6k1V9ytWmTR2BljkBdu_nFNkYlhoxpUQcbpDqsqwMl30wAvSMGlSReLemkyMzwCRK3NzSV4=">published</a> in Blood.

Syndax Pharma Publishes Data From Pivotal Phase 2 Portion Of AUGMENT-101 Trial Of Revumenib In Patients With R/R mNPM1 Acute Myeloid Leukemia In Blood

<h3>Gainers</h3>
<ul>
<li>Regencell Bioscience (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/RGC#NASDAQ">RGC</a>) shares rose 125.8% to $209.7 during Tuesday's regular session. The market value of their outstanding shares is at $2.7 billion. </li>
<li>China SXT Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SXTC#NASDAQ">SXTC</a>) shares increased by 32.66% to $1.87. The company's market cap stands at $25.7 million. </li>
<li>Tiziana Life Sciences (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/TLSA#NASDAQ">TLSA</a>) shares moved upwards by 28.27% to $1.56. The company's market cap stands at $182.8 million. </li>
<li>CareCloud (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CCLD#NASDAQ">CCLD</a>) stock moved upwards by 26.68% to $2.22. The company's market cap stands at $93.8 million. The company's, Q1 earnings came out today. </li>
<li>Cyclacel Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CYCC#NASDAQ">CYCC</a>) stock moved upwards by 20.02% to $0.36. The market value of their outstanding shares is at $4.9 million. </li>
<li>AquaBounty Techs (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AQB#NASDAQ">AQB</a>) stock increased by 18.37% to $0.76. The market value of their outstanding shares is at $2.9 million. </li>
</ul>
<h3>Losers</h3>
<ul>
<li>NuCana (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NCNA#NASDAQ">NCNA</a>) stock declined by 67.2% to $0.36 during Tuesday's regular session. The market value of their outstanding shares is at $2.1 million. </li>
<li>bioAffinity Technologies (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BIAF#NASDAQ">BIAF</a>) stock fell 44.74% to $0.21. The company's market cap stands at $3.8 million. </li>
<li>Tactile Systems Tech (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/TCMD#NASDAQ">TCMD</a>) stock decreased by 31.53% to $9.54. The company's market cap stands at $225.8 million. The company's, Q1 earnings came out yesterday. </li>
<li>Kodiak Sciences (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/KOD#NASDAQ">KOD</a>) shares fell 21.24% to $3.88. The company's market cap stands at $204.4 million. </li>
<li>Syndax Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SNDX#NASDAQ">SNDX</a>) shares declined by 21.15% to $10.7. The company's market cap stands at $913.3 million. The company's, Q1 earnings came out yesterday. </li>
<li>HealthStream (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/HSTM#NASDAQ">HSTM</a>) shares fell 18.75% to $27.01. The company's market cap stands at $824.4 million. As per the press release, Q1 earnings came out yesterday. 
See Also: <a href="http://www.benzinga.com/money/best-healthcare-stocks/" title="www.benzinga.com/money/best-healthcare-stocks/">www.benzinga.com/money/best-healthcare-stocks/</a></li>
</ul>
This article was generated by Benzinga's automated content engine and reviewed by an editor.

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12 Health Care Stocks Moving In Tuesday's Intraday Session

Scotiabank analyst George Farmer maintains Syndax Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SNDX#NASDAQ">SNDX</a>) with a Sector Perform and raises the price target from $16 to $17.

Price Target

Analyst Ratings

Scotiabank Maintains Sector Perform on Syndax Pharmaceuticals, Raises Price Target to $17

Guggenheim analyst Michael Schmidt reiterates Syndax Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SNDX#NASDAQ">SNDX</a>) with a Buy and maintains $32 price target.

Reiteration

Guggenheim Reiterates Buy on Syndax Pharmaceuticals, Maintains $32 Price Target

Syndax Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SNDX#NASDAQ">SNDX</a>) reported quarterly losses of $(0.98) per share which beat the analyst consensus estimate of $(1.03) by 4.85 percent. This is a 15.29 percent decrease over losses of $(0.85) per share from the same period last year. The company reported quarterly sales of $20.04 million which beat the analyst consensus estimate of $14.43 million by 38.86 percent.

Earnings

Earnings Beats

Syndax Pharmaceuticals Q1 EPS $(0.98) Beats $(1.03) Estimate, Sales $20.04M Beat $14.43M Estimate

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Hims & Hers Health, Inc. Class A Common Stock

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Earnings Scheduled For May 5, 2025

U.S. stock futures were higher this morning, with the Dow futures gaining around 100 points on Tuesday.
Shares of NXP Semiconductors N.V. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NXPI#NASDAQ">NXPI</a>) fell sharply in today's pre-market trading after the company reported first-quarter financial results and issued second-quarter EPS guidance with its <a href="https://in.benzinga.com/news/management/25/04/45053723/nxp-semiconductors-reports-q1-earnings-very-uncertain-operating-environment-tied-to-tariffs-ceo-transition-shares-fall">midpoint below estimates</a>.
NXP reported first-quarter revenue of $2.84 billion, in line with analyst estimates, according to Benzinga Pro. The company reported first-quarter adjusted earnings of $2.64 per share, beating analyst estimates of $2.58 per share.
NXP expects second-quarter revenue of $2.8 billion to $3 billion versus estimates of $2.87 billion. The company sees second-quarter adjusted earnings in the range of $2.46 to $2.86 per share versus estimates of $2.65 per share. The company announced CEO Kurt Sievers will retire at the end of 2025.
NXP Semiconductors shares dipped 7.7% to $181.18 in the pre-market trading session.
Here are some other stocks moving lower in pre-market trading.
<ul>
<li>Ultra Clean Holdings, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/UCTT#NASDAQ">UCTT</a>) fell 10.3% to $20.00 in pre-market trading after the company reported worse-than-expected first-quarter financial result and issued second-quarter guidance below estimates.</li>
<li>Hope Bancorp, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/HOPE#NASDAQ">HOPE</a>) declined 9.5% to $9.02 in pre-market trading.</li>
<li>Brinker International, Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/EAT#NYSE">EAT</a>) dipped 8.6% to $146.90 in pre-market trading following third-quarter results.</li>
<li>Spotify Technology S.A. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/SPOT#NYSE">SPOT</a>) fell 8.5% to $547.00 in pre-market trading after the company reported worse-than-expected quarterly earnings.</li>
<li>Syndax Pharmaceuticals, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SNDX#NASDAQ">SNDX</a>) fell 7.5% to $12.42 in pre-market trading. Syndax Pharmaceuticals will report its first quarter financial results and provide a business update on Monday, May 5.</li>
<li>Regeneron Pharmaceuticals, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/REGN#NASDAQ">REGN</a>) fell 7% to $568.00 in pre-market trading following weak quarterly earnings.</li>
<li>Sanmina Corporation (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SANM#NASDAQ">SANM</a>) fell 5.8% to $76.00 in today's pre-market trading. Sanmina posted upbeat results for its second quarter, but issued weak forecast for the third quarter. The company said it sees third-quarter adjusted earnings of $1.35 to $1.45 per share, versus market estimates of $1.53 per share. It also expects sales of $1.925 billion to $2.025 billion for the current quarter, versus market projections of $2.06 billion.</li>
<li>XPeng Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/XPEV#NYSE">XPEV</a>) fell 4.7% to $18.99 in pre-market trading.</li>
<li>BP p.l.c. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BP#NYSE">BP</a>) declined 4.3% to $27.87 in pre-market trading following first-quarter earnings.</li>
<li>AstraZeneca PLC (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AZN#NASDAQ">AZN</a>) fell 2.8% to $67.96 in pre-market trading following quarterly results.</li>
</ul>
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</ul>
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Pre-Market Outlook

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NXP Semiconductors, Brinker International, Ultra Clean, Sanmina And Other Big Stocks Moving Lower In Tuesday's Pre-Market Session

Shares of Leggett &amp; Platt, Incorporated (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/LEG#NYSE">LEG</a>) rose sharply in pre-market trading after the company reported better-than-expected first-quarter EPS results and <a href="https://www.benzinga.com/quote/LEG/earnings">raised its FY25 EPS guidance</a>.
Leggett &amp; Platt reported quarterly earnings of 24 cents per share which beat the analyst consensus estimate of 22 cents per share. The company reported quarterly sales of $1.02 billion which met the analyst consensus estimate.
Leggett &amp; Platt shares jumped 14.8% to $8.35 in pre-market trading.
Here are some other stocks moving in pre-market trading.
<h3 class="wp-block-heading">Gainers</h3>
<ul>
<li>Wearable Devices Ltd. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/WLDS#NASDAQ">WLDS</a>) rose 55% to $1.86 in pre-market trading after dipping around 25% on Monday.</li>
<li>LogicMark, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/LGMK#NASDAQ">LGMK</a>) surged 46.5% to $0.0189 in pre-market trading after jumping 48% on Monday.</li>
<li>Bon Natural Life Limited (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BON#NASDAQ">BON</a>) surged 43.2% to $0.0931 in pre-market trading after gaining 13% on Monday. Bon Natural Life recently announced it won a $12 million 24-month supply agreement to develop apple polyphenol-infused health solutions.</li>
<li>Tevogen Bio Holdings Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/TVGN#NASDAQ">TVGN</a>) gained 29.1% to $1.21 in pre-market trading after the company reaffirmed its oncology pipeline revenue forecast, projecting $1 billion in its launch year and a cumulative five-year estimate of $10 billion to $14 billion.</li>
<li>AGM Group Holdings Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AGMH#NASDAQ">AGMH</a>) gained 28.6% to $0.1724 in pre-market trading after jumping 175% on Monday.</li>
<li>Odyssey Marine Exploration, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/OMEX#NASDAQ">OMEX</a>) jumped 17.4% to $1.55 in pre-market trading after dipping over 12% on Monday.</li>
<li>Algoma Steel Group Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ASTL#NASDAQ">ASTL</a>) gained 15.5% to $5.90 in pre-market trading ahead of quarterly earnings.</li>
<li>Wolfspeed, Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/WOLF#NYSE">WOLF</a>) gained 14.1% to $4.71 in pre-market trading after jumping 26% on Monday.</li>
<li>Evolv Technologies Holdings, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/EVLV#NASDAQ">EVLV</a>) rose 12.3% to $4.67 in pre-market trading following better-than-expected quarterly results.</li>
</ul>
<h3 class="wp-block-heading">Losers</h3>
<ul>
<li>Incannex Healthcare Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/IXHL#NASDAQ">IXHL</a>) shares fell 65.8% to $0.2086 in pre-market trading after declining around 3% on Monday.</li>
<li>First Commonwealth Financial Corporation (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/FCF#NYSE">FCF</a>) shares dipped 21.5% to $12.01 in pre-market trading ahead of quarterly earnings.</li>
<li>National Energy Services Reunited Corp. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NESR#NASDAQ">NESR</a>) shares fell 21.3% to $5.00 in pre-market trading.</li>
<li>Intelligent Group Limited (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/INTJ#NASDAQ">INTJ</a>) fell 14.1% to $0.5792 in pre-market trading after dipping 12% on Monday.</li>
<li>PTL Limited (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/PTLE#NASDAQ">PTLE</a>) shares tumbled 14% to $1.17 in pre-market trading after gaining around 9% on Monday.</li>
<li>Ultra Clean Holdings, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/UCTT#NASDAQ">UCTT</a>) fell 10.3% to $20.00 in pre-market trading after the company reported worse-than-expected first-quarter financial result and issued second-quarter guidance below estimates.</li>
<li>Hope Bancorp, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/HOPE#NASDAQ">HOPE</a>) declined 9.5% to $9.02 in pre-market trading.</li>
<li>NXP Semiconductors N.V. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NXPI#NASDAQ">NXPI</a>) dipped 7.7% to $181.18 in pre-market trading after the company reported first-quarter financial results and issued second-quarter EPS guidance with its midpoint below estimates. The company announced CEO Kurt Sievers will retire at the end of 2025.</li>
<li>Syndax Pharmaceuticals, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SNDX#NASDAQ">SNDX</a>) fell 7.5% to $12.42 in pre-market trading. Syndax Pharmaceuticals will report its first quarter financial results and provide a business update on Monday, May 5.</li>
<li>Sanmina Corporation (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SANM#NASDAQ">SANM</a>) fell 5.8% to $76.00 in today's pre-market trading. Sanmina posted upbeat results for its second quarter, but issued weak forecast for the third quarter. The company said it sees third-quarter adjusted earnings of $1.35 to $1.45 per share, versus market estimates of $1.53 per share. It also expects sales of $1.925 billion to $2.025 billion for the current quarter, versus market projections of $2.06 billion.</li>
</ul>
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</ul>
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Why Leggett & Platt Shares Are Trading Higher By Around 15%; Here Are 20 Stocks Moving Premarket

JP Morgan released a survey on Thursday focused on the launch prospects of Syndax Pharmaceuticals Inc&#8217;s (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SNDX#NASDAQ">SNDX</a>) Revuforj (revumenib) in relapsed/refractory (r/r) KMT2A acute leukemias and nucleophosmin 1 mutation acute <a href="https://www.benzinga.com/general/biotech" target="_blank" rel="noreferrer noopener">myeloid leukemia (NPM1 AML)</a>.
The FDA approved Revuforj in November 2024 as the first and only menin inhibitor for r/r acute leukemia with a lysine methyltransferase 2A gene (KMT2A) translocation in adult and pediatric patients <a target="_blank" href="https://www.benzinga.com/pressreleases/24/11/n42020752/syndax-announces-fda-approval-of-revuforj-revumenib-the-first-and-only-menin-inhibitor-to-treat-ad" rel="noreferrer noopener">one year and older</a>.
Revuforj generated $7.7 million in net product revenue during its first five weeks on the market.
The company expects to submit a supplemental application filing for revumenib in R/R mNPM1 AML in the second quarter of 2025, followed by a potential FDA approval <a target="_blank" href="https://www.benzinga.com/pressreleases/25/03/g44073341/syndax-reports-fourth-quarter-and-full-year-2024-financial-results-and-provides-business-update" rel="noreferrer noopener">around year-end 2025</a>.
Also Read: <a target="_blank" href="https://www.benzinga.com/general/biotech/24/08/40396645/fda-approves-incytesyndax-partnered-drug-for-chronic-graft-versus-host-disease-a-post-transplant-" rel="noreferrer noopener">FDA Approves Incyte/Syndax Partnered Drug For Chronic Graft-Versus-Host Disease, A Post-Transplant Complication</a>
JPMorgan says that, on average, surveyed physicians treated 8 KMT2A acute leukemia and 12 NPM1 AML patients.
Overall, surveyed physicians provided high ratings related to Revuforj&#8217;s clinical profile in both r/r KMT2A acute leukemias and NPM1 AML.
Analyst Anupam Rama writes that surveyed physicians indicated a high degree of comfort using Revuforj in r/r NPM1 should the product be incorporated into NCCN guidelines.
&#8220;In our view, survey results underscore that SNDX shares are currently materially undervalued on Revuforj in the r/r (KMT2A / NPM1) setting alone – which we value in the ~high-$20 to low-$30s / share range,&#8221; Rama writes.
For the near term, JPMorgan estimates 2025 Revuforj sales to be around $50 million (US only), largely driven by the KMT2A setting.
JPMorgan raised its price target from $39 to $41, accounting for a faster ramp to peak for Revuforj in both KMT2A acute leukemias and NPM1 AML, reiterating the Overweight rating.
Price Action: SNDX stock is up 0.43% at $14.16 at last check Friday.
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Photo: Shutterstock

Analyst Color

Syndax's Revuforj Earns Strong Physician Support, JP Morgan Predicts Sales Growth

WIIM

Syndax Pharmaceuticals shares are trading higher after JP Morgan raised its price target on the stock from $39 to $41 and maintained an Overweight rating.

JP Morgan analyst Anupam Rama maintains Syndax Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SNDX#NASDAQ">SNDX</a>) with a Overweight and raises the price target from $39 to $41.

JP Morgan Maintains Overweight on Syndax Pharmaceuticals, Raises Price Target to $41

JP Morgan analyst Anupam Rama maintains Syndax Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SNDX#NASDAQ">SNDX</a>) with a Overweight and raises the price target from $35 to $39.

JP Morgan Maintains Overweight on Syndax Pharmaceuticals, Raises Price Target to $39

Citigroup analyst Yigal Nochomovitz maintains Syndax Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SNDX#NASDAQ">SNDX</a>) with a Buy and lowers the price target from $45 to $42.

Citigroup Maintains Buy on Syndax Pharmaceuticals, Lowers Price Target to $42

HC Wainwright &amp; Co. analyst Edward White reiterates Syndax Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SNDX#NASDAQ">SNDX</a>) with a Buy and maintains $51 price target.

HC Wainwright & Co. Reiterates Buy on Syndax Pharmaceuticals, Maintains $51 Price Target

Syndax Pharmaceuticals shares are trading lower after the company reported Q4 financial results and missed its EPS and sales estimate.

For the first quarter of 2025, the Company expects research and development expenses to be&nbsp;$65 to $70 million&nbsp;and total research and development plus selling, general and administrative expenses to be&nbsp;$105 to $110 million. For the full year of 2025, the Company expects research and development expenses to be&nbsp;$260 to $280 million&nbsp;and total research and development plus selling, general and administrative expenses to be&nbsp;$415 to $435 million, which includes an estimated&nbsp;$45 million&nbsp;in non-cash stock compensation expense. The Company is not providing revenue guidance at this time.

Guidance

Syndax Sees Research & Development Expenses Of $65M-$70M In Q1, $260M-$280M In 2025

Syndax Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SNDX#NASDAQ">SNDX</a>) reported quarterly losses of $(1.10) per share which missed the analyst consensus estimate of $(1.01) by 8.91 percent. This is a 10 percent decrease over losses of $(1.00) per share from the same period last year. The company reported quarterly sales of $7.68 million which missed the analyst consensus estimate of $85.91 million by 91.06 percent.

Earnings Misses

Syndax Pharmaceuticals Q4 2024 GAAP EPS $(1.10) Misses $(1.01) Estimate, Sales $7.68M Miss $85.91M Estimate

Press Releases

Syndax Announces Participation at the Stifel 2025 Virtual Targeted Oncology Forum

Syndax Pharmaceuticals Reports Inducement Grants Under NASDAQ Listing Rule 5635(c)(4)

Syndax to Announce First Quarter 2025 Financial Results and Host Conference Call and Webcast on May 5, 2025

Syndax Reports First Quarter 2025 Financial Results and Provides Business Update

Syndax Announces Publication of Pivotal Revumenib Data in Relapsed or Refractory mNPM1 Acute Myeloid Leukemia in the Journal Blood

Syndax Announces Participation in May Investor Conferences

Management

Syndax Pharmaceuticals Appoints Dr. Nicholas Botwood as Head of Research and Development and Chief Medical Officer

Health Care

Syndax Announces Data Presentations at EHA 2025 Showcasing Revuforj® (revumenib) and Niktimvo™ (axatilimab-csfr)

Comments

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