Vertex Pharmaceuticalsの空売り状況は、投資家がVertex Pharmaceuticalsの株価下落に賭けている度合いを知ることができます。空売りデータは2週間ごとに更新されます。

Vertex Pharmaceuticals (NASDAQ:VRTX) 株価情報, 空売り情報

Vertex Pharmaceuticals

Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease. Additionally, Vertex is evaluating small-molecule inhibitors targeting acute and chronic pain using nonopioid treatments, and small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.

Analyst Ratings

VRTX

Vertex Pharmaceuticals（NASDAQ:VRTX）に14人のアナリストが過去3か月間で分析を行ったところ、その視点は強気から弱気まで多様なものとなった。

14人のアナリスト分析からVertexの市場動向を追う

Vertex Pharmaceuticals Incorporated - Common Stock

Vertex Pharmaceuticals Inc

25 analysts have shared their evaluations of Vertex Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/VRTX#NASDAQ">VRTX</a>) during the recent three months, expressing a mix of bullish and bearish perspectives.
The following table encapsulates their recent ratings, offering a glimpse into the evolving sentiments over the past 30 days and comparing them to the preceding months.
<table>
<thead>
<tr>
<th></th>
<th align="right">Bullish</th>
<th align="right">Somewhat Bullish</th>
<th align="right">Indifferent</th>
<th align="right">Somewhat Bearish</th>
<th align="right">Bearish</th>
</tr>
</thead>
<tbody>
<tr>
<td>Total Ratings</td>
<td align="right">7</td>
<td align="right">7</td>
<td align="right">11</td>
<td align="right">0</td>
<td align="right">0</td>
</tr>
<tr>
<td>Last 30D</td>
<td align="right">0</td>
<td align="right">0</td>
<td align="right">1</td>
<td align="right">0</td>
<td align="right">0</td>
</tr>
<tr>
<td>1M Ago</td>
<td align="right">3</td>
<td align="right">4</td>
<td align="right">7</td>
<td align="right">0</td>
<td align="right">0</td>
</tr>
<tr>
<td>2M Ago</td>
<td align="right">1</td>
<td align="right">2</td>
<td align="right">1</td>
<td align="right">0</td>
<td align="right">0</td>
</tr>
<tr>
<td>3M Ago</td>
<td align="right">3</td>
<td align="right">1</td>
<td align="right">2</td>
<td align="right">0</td>
<td align="right">0</td>
</tr>
</tbody>
</table>
Insights from analysts' 12-month price targets are revealed, presenting an average target of $479.6, a high estimate of $550.00, and a low estimate of $407.00. This current average represents a 1.63% decrease from the previous average price target of $487.56. 
<img src="https://www.benzinga.com/files/images/story/2025/1740085227_0.png" alt="price target chart" />
<h2>Decoding Analyst Ratings: A Detailed Look</h2>
The analysis of recent analyst actions sheds light on the perception of Vertex Pharmaceuticals by financial experts. The following summary presents key analysts, their recent evaluations, and adjustments to ratings and price targets.
<table>
<thead>
<tr>
<th>Analyst</th>
<th>Analyst Firm</th>
<th>Action Taken</th>
<th>Rating</th>
<th>Current Price Target</th>
<th>Prior Price Target</th>
</tr>
</thead>
<tbody>
<tr>
<td>Brian Abrahams</td>
<td>RBC Capital</td>
<td>Raises</td>
<td>Sector Perform</td>
<td>$408.00</td>
<td>$407.00</td>
</tr>
<tr>
<td>Whitney Ijem</td>
<td>Canaccord Genuity</td>
<td>Raises</td>
<td>Hold</td>
<td>$424.00</td>
<td>$408.00</td>
</tr>
<tr>
<td>Joon Lee</td>
<td>Truist Securities</td>
<td>Raises</td>
<td>Buy</td>
<td>$520.00</td>
<td>$460.00</td>
</tr>
<tr>
<td>Brian Abrahams</td>
<td>RBC Capital</td>
<td>Raises</td>
<td>Sector Perform</td>
<td>$407.00</td>
<td>$402.00</td>
</tr>
<tr>
<td>Greg Harrison</td>
<td>Scotiabank</td>
<td>Raises</td>
<td>Sector Perform</td>
<td>$450.00</td>
<td>$433.00</td>
</tr>
<tr>
<td>Olivia Brayer</td>
<td>Cantor Fitzgerald</td>
<td>Maintains</td>
<td>Overweight</td>
<td>$480.00</td>
<td>$480.00</td>
</tr>
<tr>
<td>Gena Wang</td>
<td>Barclays</td>
<td>Raises</td>
<td>Equal-Weight</td>
<td>$467.00</td>
<td>$435.00</td>
</tr>
<tr>
<td>Andrew Fein</td>
<td>HC Wainwright &amp; Co.</td>
<td>Maintains</td>
<td>Buy</td>
<td>$550.00</td>
<td>$550.00</td>
</tr>
<tr>
<td>Matthew Harrison</td>
<td>Morgan Stanley</td>
<td>Raises</td>
<td>Equal-Weight</td>
<td>$459.00</td>
<td>$450.00</td>
</tr>
<tr>
<td>Olivia Brayer</td>
<td>Cantor Fitzgerald</td>
<td>Maintains</td>
<td>Overweight</td>
<td>$480.00</td>
<td>$480.00</td>
</tr>
<tr>
<td>Greg Harrison</td>
<td>Scotiabank</td>
<td>Raises</td>
<td>Sector Perform</td>
<td>$433.00</td>
<td>$430.00</td>
</tr>
<tr>
<td>Andrew Fein</td>
<td>HC Wainwright &amp; Co.</td>
<td>Raises</td>
<td>Buy</td>
<td>$550.00</td>
<td>$535.00</td>
</tr>
<tr>
<td>Mohit Bansal</td>
<td>Wells Fargo</td>
<td>Maintains</td>
<td>Equal-Weight</td>
<td>$460.00</td>
<td>$460.00</td>
</tr>
<tr>
<td>Christopher Raymond</td>
<td>Piper Sandler</td>
<td>Lowers</td>
<td>Overweight</td>
<td>$533.00</td>
<td>$535.00</td>
</tr>
<tr>
<td>Olivia Brayer</td>
<td>Cantor Fitzgerald</td>
<td>Maintains</td>
<td>Overweight</td>
<td>$480.00</td>
<td>$480.00</td>
</tr>
<tr>
<td>Mohit Bansal</td>
<td>Wells Fargo</td>
<td>Lowers</td>
<td>Overweight</td>
<td>$460.00</td>
<td>$555.00</td>
</tr>
<tr>
<td>Joon Lee</td>
<td>Truist Securities</td>
<td>Lowers</td>
<td>Buy</td>
<td>$460.00</td>
<td>$550.00</td>
</tr>
<tr>
<td>Greg Harrison</td>
<td>Scotiabank</td>
<td>Raises</td>
<td>Sector Perform</td>
<td>$430.00</td>
<td>$426.00</td>
</tr>
<tr>
<td>Jessica Fye</td>
<td>JP Morgan</td>
<td>Lowers</td>
<td>Overweight</td>
<td>$500.00</td>
<td>$503.00</td>
</tr>
<tr>
<td>Gena Wang</td>
<td>Barclays</td>
<td>Lowers</td>
<td>Equal-Weight</td>
<td>$418.00</td>
<td>$509.00</td>
</tr>
<tr>
<td>Evan Seigerman</td>
<td>BMO Capital</td>
<td>Lowers</td>
<td>Outperform</td>
<td>$520.00</td>
<td>$566.00</td>
</tr>
<tr>
<td>Andrew Fein</td>
<td>HC Wainwright &amp; Co.</td>
<td>Lowers</td>
<td>Buy</td>
<td>$535.00</td>
<td>$600.00</td>
</tr>
<tr>
<td>Ying Huang</td>
<td>B of A Securities</td>
<td>Lowers</td>
<td>Buy</td>
<td>$522.00</td>
<td>$545.00</td>
</tr>
<tr>
<td>Paul Matteis</td>
<td>Stifel</td>
<td>Raises</td>
<td>Hold</td>
<td>$494.00</td>
<td>$490.00</td>
</tr>
<tr>
<td>Michael Yee</td>
<td>Jefferies</td>
<td>Raises</td>
<td>Buy</td>
<td>$550.00</td>
<td>$500.00</td>
</tr>
</tbody>
</table>
<h3>Key Insights:</h3>
<ul>
<li>Action Taken: Analysts frequently update their recommendations based on evolving market conditions and company performance. Whether they 'Maintain', 'Raise' or 'Lower' their stance, it reflects their reaction to recent developments related to Vertex Pharmaceuticals. This information provides a snapshot of how analysts perceive the current state of the company.</li>
<li>Rating: Analysts assign qualitative assessments to stocks, ranging from 'Outperform' to 'Underperform'. These ratings convey the analysts' expectations for the relative performance of Vertex Pharmaceuticals compared to the broader market.</li>
<li>Price Targets: Analysts gauge the dynamics of price targets, providing estimates for the future value of Vertex Pharmaceuticals's stock. This comparison reveals trends in analysts' expectations over time.</li>
</ul>
Assessing these analyst evaluations alongside crucial financial indicators can provide a comprehensive overview of Vertex Pharmaceuticals's market position. Stay informed and make well-judged decisions with the assistance of our Ratings Table.
<a href="https://www.benzinga.com/quote/VRTX/analyst-ratings?utm_source=benzinga-insights&amp;adType=benzinga-insights&amp;ad=analyst-ratings&amp;campaign=wallstreetadvantage">Stay up to date on Vertex Pharmaceuticals analyst ratings.</a>
<h2>Discovering Vertex Pharmaceuticals: A Closer Look</h2>
Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease. Additionally, Vertex is evaluating small-molecule inhibitors targeting acute and chronic pain using nonopioid treatments, and small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
<h3>Vertex Pharmaceuticals's Financial Performance</h3>
Market Capitalization Analysis: With an elevated market capitalization, the company stands out above industry averages, showcasing substantial size and market acknowledgment.
Revenue Growth: Vertex Pharmaceuticals's revenue growth over a period of 3 months has been noteworthy. As of 31 December, 2024, the company achieved a revenue growth rate of approximately 15.66%. This indicates a substantial increase in the company's top-line earnings. As compared to competitors, the company surpassed expectations with a growth rate higher than the average among peers in the Health Care sector.
Net Margin: The company's net margin is below industry benchmarks, signaling potential difficulties in achieving strong profitability. With a net margin of 31.35%, the company may need to address challenges in effective cost control.
Return on Equity (ROE): The company's ROE is a standout performer, exceeding industry averages. With an impressive ROE of 5.7%, the company showcases effective utilization of equity capital.
Return on Assets (ROA): Vertex Pharmaceuticals's ROA stands out, surpassing industry averages. With an impressive ROA of 4.08%, the company demonstrates effective utilization of assets and strong financial performance.
Debt Management: With a below-average debt-to-equity ratio of 0.11, Vertex Pharmaceuticals adopts a prudent financial strategy, indicating a balanced approach to debt management.
<h2>The Basics of Analyst Ratings</h2>
Ratings come from analysts, or specialists within banking and financial systems that report for specific stocks or defined sectors (typically once per quarter for each stock). Analysts usually derive their information from company conference calls and meetings, financial statements, and conversations with important insiders to reach their decisions.
Some analysts publish their predictions for metrics such as growth estimates, earnings, and revenue to provide additional guidance with their ratings. When using analyst ratings, it is important to keep in mind that stock and sector analysts are also human and are only offering their opinions to investors.
If you want to keep track of which analysts are outperforming others, you can view updated analyst ratings along withanalyst success scores in <a href="https://www.benzinga.com/pro/">Benzinga Pro</a>.
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Analyst Expectations For Vertex Pharmaceuticals's Future

RBC Capital analyst Brian Abrahams maintains Vertex Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/VRTX#NASDAQ">VRTX</a>) with a Sector Perform and raises the price target from $407 to $408.

News

Price Target

RBC Capital Maintains Sector Perform on Vertex Pharmaceuticals, Raises Price Target to $408

Top Wall Street analysts changed their outlook on these top names. For a complete view of all analyst rating changes, including upgrades, downgrades and initiations, please see our <a href="https://www.benzinga.com/analyst-stock-ratings">analyst ratings page</a>.
<ul>
<li>Raymond James analyst C. Gregory Peters upgraded the rating for Mercury General Corporation (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/MCY#NYSE">MCY</a>) from Outperform to Strong Buy and raised the price target from $70 to $80. Mercury General shares closed at $50.09 on Tuesday. <a href="https://www.benzinga.com/quote/MCY/analyst-ratings">See how other analysts view this stock</a>.</li>
<li>JP Morgan analyst Reginald Smith upgraded Upstart Holdings, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/UPST#NASDAQ">UPST</a>) from Underweight to Neutral and boosted the price target from $57 to $79. Upstart shares closed at $67.34 on Tuesday. <a href="https://www.benzinga.com/quote/upst/analyst-ratings">See how other analysts view this stock</a>.</li>
<li>Morgan Stanley analyst Joseph Moore upgraded the rating for NXP Semiconductors N.V. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NXPI#NASDAQ">NXPI</a>) from Equal-Weight to Overweight and increased the price target from $231 to $257. NXP Semiconductors shares closed at $210.97 on Tuesday. <a href="https://www.benzinga.com/quote/nxpi/analyst-ratings">See how other analysts view this stock</a>.</li>
<li>Needham analyst Quinn Bolton upgraded GLOBALFOUNDRIES Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/GFS#NASDAQ">GFS</a>) from Hold to Buy and announced a $50 price target. Maplebear shares closed at $40.10 on Tuesday. <a href="https://www.benzinga.com/quote/gfs/analyst-ratings">See how other analysts view this stock</a>.</li>
<li>Canaccord Genuity analyst Whitney Ijem upgraded the rating for Vertex Pharmaceuticals Incorporated (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/VRTX#NASDAQ">VRTX</a>) from Sell to Hold and raised the price target from $408 to $424. Vertex Pharmaceuticals shares closed at $455.22 on Tuesday. <a href="https://www.benzinga.com/quote/vrtx/analyst-ratings">See how other analysts view this stock.</a></li>
</ul>
Considering buying NXPI stock? Here&#8217;s what analysts think: 
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Upgrades

Pre-Market Outlook

Markets

Trading Ideas

NXPI

UPST

This NXP Semiconductors Analyst Turns Bullish; Here Are Top 5 Upgrades For Wednesday

Canaccord Genuity analyst Whitney Ijem upgrades Vertex Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/VRTX#NASDAQ">VRTX</a>) from Sell to Hold and raises the price target from $408 to $424.

Canaccord Genuity Upgrades Vertex Pharmaceuticals to Hold, Raises Price Target to $424

Truist Securities analyst Joon Lee maintains Vertex Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/VRTX#NASDAQ">VRTX</a>) with a Buy and raises the price target from $460 to $520.

Truist Securities Maintains Buy on Vertex Pharmaceuticals, Raises Price Target to $520

RBC Capital analyst Brian Abrahams maintains Vertex Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/VRTX#NASDAQ">VRTX</a>) with a Sector Perform and raises the price target from $402 to $407.

RBC Capital Maintains Sector Perform on Vertex Pharmaceuticals, Raises Price Target to $407

Vertex Pharmaceuticals Incorporated (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/VRTX#NASDAQ">VRTX</a>) reported mixed results for its fourth <a href="https://www.benzinga.com/quote/VRTX/earnings">quarter on Monday</a>.
The company posted quarterly adjusted earnings of $3.48 per share which missed the analyst consensus estimate of $4.03 per share. The company reported quarterly sales of $2.912 billion which beat the analyst consensus estimate of $2.781 billion.
&#8220;2024 marked a year of tremendous growth for Vertex and we anticipate 2025 will be another important year with the landmark JOURNAVX approval and launch for moderate-to-severe acute pain; the launch of our fifth CF medicine, ALYFTREK; the continuing global launch of CASGEVY; and multiple ongoing pivotal trials. We are excited to drive diversification of the revenue base, disease areas of focus, R&amp;D pipeline, and geographies to continue to deliver long-term value to both patients and shareholders,&#8221; said Reshma Kewalramani, M.D., Chief Executive Officer and President of Vertex.
Vertex Pharmaceuticals said it sees FY25 revenue of $11.75 billion to $12.00 billion, versus market estimates of $11.84 billion.
Vertex Pharmaceuticals shares fell 2.5% to trade at $458.15 on Tuesday.
These analysts made changes to their price targets on Vertex Pharmaceuticals following earnings announcement.
<ul>
<li>Morgan Stanley analyst Matthew Harrison maintained Vertex Pharmaceuticals with an Equal-Weight and raised the price target from $450 to $459.</li>
<li>Barclays analyst Gena Wang maintained the stock with an Equal-Weight and raised the price target from $435 to $46.</li>
<li>HC Wainwright &amp; Co. analyst Andrew Fein, meanwhile, reiterated Vertex Pharmaceuticals with a Buy and maintained a $550 price target.</li>
</ul>
Considering buying VRTX stock? Here&#8217;s what analysts think: 
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Earnings

Vertex Pharmaceuticals Analysts Increase Their Forecasts After Q4 Results

Scotiabank analyst Greg Harrison maintains Vertex Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/VRTX#NASDAQ">VRTX</a>) with a Sector Perform and raises the price target from $433 to $450.

Scotiabank Maintains Sector Perform on Vertex Pharmaceuticals, Raises Price Target to $450

Cantor Fitzgerald analyst Olivia Brayer reiterates Vertex Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/VRTX#NASDAQ">VRTX</a>) with a Overweight and maintains $480 price target.

Reiteration

Cantor Fitzgerald Reiterates Overweight on Vertex Pharmaceuticals, Maintains $480 Price Target

Barclays analyst Gena Wang maintains Vertex Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/VRTX#NASDAQ">VRTX</a>) with a Equal-Weight and raises the price target from $435 to $467.

Barclays Maintains Equal-Weight on Vertex Pharmaceuticals, Raises Price Target to $467

HC Wainwright &amp; Co. analyst Andrew Fein reiterates Vertex Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/VRTX#NASDAQ">VRTX</a>) with a Buy and maintains $550 price target.

HC Wainwright & Co. Reiterates Buy on Vertex Pharmaceuticals, Maintains $550 Price Target

Morgan Stanley analyst Matthew Harrison maintains Vertex Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/VRTX#NASDAQ">VRTX</a>) with a Equal-Weight and raises the price target from $450 to $459.

Morgan Stanley Maintains Equal-Weight on Vertex Pharmaceuticals, Raises Price Target to $459

Needham analyst Joseph Stringer reiterates Vertex Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/VRTX#NASDAQ">VRTX</a>) from Hold to Hold.

Needham Reiterates Hold on Vertex Pharmaceuticalsto Hold

Management

Vertex COO Stuart Arbuckle To Retire Jul. 2025

Guidance

Vertex Pharmaceuticals Sees FY25 Revenue $11.75B-$12.00B vs. $11.84B Est.

Earnings Beats

Earnings Misses

Vertex Pharmaceuticals Q4 2024 Adj. EPS $3.98 Misses $4.03 Estimate

Vertex Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/VRTX#NASDAQ">VRTX</a>) reported quarterly earnings of $3.50 per share which missed the analyst consensus estimate of $3.57 by 1.96 percent. The company reported quarterly sales of $2.912 billion which beat the analyst consensus estimate of $2.781 billion by 4.70 percent. This is a 15.66 percent increase over sales of $2.518 billion the same period last year.

Vertex Pharmaceuticals Q4 2024 GAAP EPS $3.50 Misses $3.57 Estimate, Sales $2.912B Beat $2.781B Estimate

CDNA

NTRA

Live On CNBC, Amy Raskin Announces Trimmed Vertex Pharmaceuticals ; Trimmed Kadant Position; Trimmed Natera Position; Bought CareDx

Vertex Pharmaceuticals Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/VRTX#NASDAQ">VRTX</a>) is set to report <a href="https://www.benzinga.com/quote/VRTX/earnings">fourth quarter earnings</a> after the market closes Monday. Biotech investors are bracing for impact.
<figure class="wp-block-image size-full"><a href="https://bzresearch.myclickfunnels.com/benzinga-pro-content-webinar-registration/?utm_source=BZprocontent021025&amp;t=be2bearmibe3na1"><img loading="lazy" decoding="async" width="631" height="486" src="https://editorial-assets.benzinga.com/wp-content/uploads/2025/02/10085744/Screenshot-2025-02-10-at-7.27.22-PM.png" alt="" class="wp-image-774596" srcset="https://editorial-assets.benzinga.com/wp-content/uploads/2025/02/10085744/Screenshot-2025-02-10-at-7.27.22-PM.png 631w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/02/10085744/Screenshot-2025-02-10-at-7.27.22-PM-300x231.png 300w" sizes="(max-width: 631px) 100vw, 631px" /></a></figure>
<a href="https://bzresearch.myclickfunnels.com/benzinga-pro-content-webinar-registration/?utm_source=BZprocontent021025&amp;t=be2bearmibe3na1">Chart created using Benzinga Pro</a>
The stock has climbed 15.66% year-to-date, recovering from last year's volatility. With selling pressure creeping in, the question is whether this rally has legs, or if it&#8217;s time for a reset.
<h2 class="wp-block-heading">Wall Street's Expectations: Solid Numbers Or A Reality Check?</h2>
Wall Street expects Vertex to post EPS of $4.03 on revenue of $2.78 billion, per <a href="https://bzresearch.myclickfunnels.com/benzinga-pro-content-webinar-registration/?utm_source=BZprocontent021025&amp;t=be2bearmibe3na1">Benzinga Pro</a> data. 
But beyond the numbers, the real focus is on the company's upcoming drug launches and how they could fuel future growth.
Read Also: <a href="https://www.benzinga.com/trading-ideas/long-ideas/25/02/43526731/unitedhealth-vertex-pharmaceuticals-axon-enterprise-and-a-major-energy-stock-cnbcs-final-trades">UnitedHealth, Vertex Pharmaceuticals, Axon Enterprise And A Major Energy Stock: CNBC&#8217;s &#8216;Final Trades&#8217;</a>
<h2 class="wp-block-heading">Pipeline Watch: Can Alyftrek And Suzetrigine Deliver?</h2>
JPMorgan analyst Jessica Fye sees 2025 as a make-or-break year for Vertex.
The company is rolling out Alyftrek, its latest cystic fibrosis (CF) treatment and preparing for a potential suzetrigine launch in acute pain. Investors will be watching management's commentary on these new products closely, especially after suzetrigine's mixed Phase II results in LSR (large sensory neuropathy).
Fye expects a solid launch for Alyftrek, modeling $376 million in 2025 revenue though but suzetrigine's adoption remains uncertain, with pricing a key factor.
<h2 class="wp-block-heading">VRTX Stock Technicals: Bullish, But With Risks</h2>
Technicals are giving mixed signals. VRTX stock is trading at $469.32, above its eight-day, 20-day, 50-day and 200-day moving averages, flashing buy signals across the board.
The MACD (moving average convergence/divergence) indicator is bullish. RSI (relative strength index) at 62.06 suggests there&#8217;s still room to run.
But selling pressure is creeping in, hinting at potential turbulence ahead.
<h2 class="wp-block-heading">Can Vertex Stock Keep Its Momentum?</h2>
Vertex needs to deliver more than just a solid quarter though investors want confidence in its 2025 pipeline. Any slip-up in guidance could shake the stock's recent momentum. Stay tuned.
Read Next:
<ul>
<li><a href="https://www.benzinga.com/analyst-ratings/price-target/25/02/43589292/top-wall-street-forecasters-revamp-vertex-pharmaceuticals-price-expectations-ahead-of-q4-earnings">Top Wall Street Forecasters Revamp Vertex Pharmaceuticals Price Expectations Ahead Of Q4 Earnings</a></li>
</ul>
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Vertex Q4 Earnings On Deck: Will This Biotech Heavyweight Keep Its Edge?

Vertex Pharmaceuticals Incorporated (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/VRTX#NASDAQ">VRTX</a>) will release its fourth-quarter financial results, after the <a href="https://www.benzinga.com/quote/vrtx/earnings">closing bell, on Monday, Feb. 10, 2025.</a>
Analysts expect the Boston, Massachusetts-based company to report quarterly earnings at $4.02 per share, down from $4.20 per share in the year-ago period. Vertex Pharmaceuticals projects quarterly revenue of $2.78 billion, compared to $2.52 billion a year earlier, according to data from <a href="https://pro.benzinga.com/dashboard">Benzinga Pro</a>.
On Jan. 30, Vertex Pharmaceuticals announced it secured FDA approval for JOURNAVX. Also, the company announced a reimbursement agreement with NHS England for eligible sickle cell disease patients to access CASGEVY.
Vertex Pharmaceuticals shares fell 2.5% to close at $469.32 on Friday.
Benzinga readers can access the latest analyst ratings on the <a href="https://www.benzinga.com/analyst-ratings/analyst-color/22/09/28888638/exclusive-study-finds-benzinga-analyst-ratings-data-yields-market-beating-strategie">Analyst Stock Rating</a> page. Readers can sort by stock ticker, company name, analyst firm, rating change or other variables.
Let's have a look at how Benzinga's most-accurate <a href="https://www.benzinga.com/quote/VRTX/analyst-ratings">analysts have rated the company</a> in the recent period.
<ul>
<li>HC Wainwright &amp; Co. analyst Andrew Fein maintained a Buy rating and raised the price target from $535 to $550 on Jan. 31, 2025. This analyst has an accuracy rate of 61%.</li>
<li>Wells Fargo analyst Mohit Bansal downgraded the stock from Overweight to Equal-Weight with a price target of $460 on Jan. 30, 2025. This analyst has an accuracy rate of 73%.</li>
<li>Truist Securities analyst Joon Lee maintained a Buy rating and lowered the price target from $550 to $460 on Dec. 23, 2024. This analyst has an accuracy rate of 76%.</li>
<li>JP Morgan analyst Jessica Fye maintained an Overweight rating and cut the price target from $503 to $500 on Dec. 23, 2024. This analyst has an accuracy rate of 63%.</li>
<li>BMO Capital analyst Even Seigerman maintained an Outperform rating and cut the price target from $566 to $520 on Dec. 20, 2024. This analyst has an accuracy rate of 62%.</li>
</ul>
Considering buying VRTX stock? Here&#8217;s what analysts think: 
<figure class="wp-block-image size-large is-resized"><img loading="lazy" decoding="async" width="1024" height="626" src="https://editorial-assets.benzinga.com/wp-content/uploads/2025/02/10041419/image-73-1024x626.png" alt="" class="wp-image-774084" style="width:543px;height:auto" srcset="https://editorial-assets.benzinga.com/wp-content/uploads/2025/02/10041419/image-73-1024x626.png 1024w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/02/10041419/image-73-300x183.png 300w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/02/10041419/image-73-768x469.png 768w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/02/10041419/image-73.png 1131w" sizes="(max-width: 1024px) 100vw, 1024px" /></figure>
Read This Next: 
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<li><a href="https://www.benzinga.com/trading-ideas/long-ideas/25/02/43559194/jim-cramer-likes-this-utilities-stock-i-think-youve-got-a-good-one">Jim Cramer Likes This Utilities Stock: &#8216;I Think You&#8217;ve Got A Good One&#8217;</a></li>
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Top Wall Street Forecasters Revamp Vertex Pharmaceuticals Price Expectations Ahead Of Q4 Earnings

Press Releases

Zai Lab and Vertex Announce Strategic Agreement to Develop and Commercialize Povetacicept in Mainland China, Hong Kong SAR, Macau SAR, Taiwan region and Singapore

Vertex and Zai Lab Announce Strategic Agreement to Develop and Commercialize Povetacicept in Mainland China, Hong Kong SAR, Macau SAR, Taiwan Region and Singapore

Vertex Provides Pipeline and Business Updates in Advance of Upcoming Investor Meetings

Economics

Antibody Drug Conjugates Market Size is Expected to Reach USD 25.38 Billion by 2033, Growing at a CAGR of 8.84%: Straits Research

Vertex to Announce Fourth Quarter and Full Year 2024 Financial Results on February 10

Vertex Announces FDA Approval of JOURNAVX™ (suzetrigine), a First-in-Class Treatment for Adults With Moderate-to-Severe Acute Pain

Vertex Announces CASGEVY® Reimbursement Agreement for the Treatment of Sickle Cell Disease in England

Vertex Reports Fourth Quarter and Full Year 2024 Financial Results

AM Best Assigns Credit Ratings to Torreyana Insurance Company, Inc.

Vertex to Participate in Upcoming March Investor Conferences

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